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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (24%), Rat (24%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-61498. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Possesses 3'-5' exoribonuclease activity. Required for 3'-end trimming of AGO1-bound miRNAs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Exonuclease 3'-5' domain-containing protein 3; Exonuclease mut-7 homolog; probable exonuclease mut-7 homolog, isoform 5; testicular tissue protein Li 125
Gene Aliases: EXD3; HBE269; mut-7
UniProt ID: (Human) Q8N9H8
Entrez Gene ID: (Human) 54932
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