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Invitrogen
Human FAM73A (aa 279-405) Control Fragment Recombinant Protein
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Product Details
RP-90528
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
QEEFEATLGASDPNSLADDIDKDTDITMKGNVEDFGLRDTLSIASTDSFASAAELAEHREVRHTYSLESLCHCPFYEEAMHLVEEGKIYSRVLRTEMLECLGDSDFLAKLHCIRQAFQVILSESANR
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
1M urea/PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (73%), Rat (73%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-53611. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
The FAM73A gene, also known as Family With Sequence Similarity 73 Member A, is located on chromosome 2q33.3. This gene encodes a protein embedded in cellular membranes and is recognized for its involvement in various cellular processes including signal transduction and cell communication. FAM73A has been observed to play a significant role in the regulation of cancer stem cell-like properties, particularly in gastric cancer, where its circular RNA form (circFAM73A) has been implicated in tumor progression. Additionally, FAM73A is involved in iron homeostasis and resistance mechanisms within the cell, suggesting its participation in broader metabolic and stress response pathways. The gene includes multiple exons and is subject to alternative splicing, which yields various transcript variants, enhancing its functional diversity within different cellular contexts.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: family with sequence similarity 73 member A; family with sequence similarity 73, member A; Mitoguardin 1; Protein FAM73A
Gene Aliases: FAM73A; MIGA1
UniProt ID: (Human) Q8NAN2
Entrez Gene ID: (Human) 374986
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