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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (45%), Rat (45%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-56989. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene encodes a cancer-testis antigen that is highly expressed in hepatocellular carcinomas and other tumors and weakly expressed in normal tissues except testis. The protein is strongly expressed in spermatogonia, primary spermatocytes, and Sertoli cells in seminiferous tubules. This protein may have a role in the control of early testicular differentiation and cell proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BJ-HCC-2 antigen; Cancer/testis antigen 43; CT43; fetal and adult testis expressed transcript protein; Fetal and adult testis-expressed transcript protein; Tumor antigen BJ-HCC-2
Gene Aliases: CT43; FATE; FATE1
UniProt ID: (Human) Q969F0
Entrez Gene ID: (Human) 89885
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