Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
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This peptide corresponds to 16 amino acids near the carboxy terminus of human FLASH.
PEP-0079 can be used as a blocking peptide with polyclonal antibody PA5-19954.
This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CASP8 associated protein 2; CASP8-associated protein 2; CASP8AP2; FLASH homolog RIP25; FLICE associated huge; FLICE-associated huge protein; FLJ11208; human FLASH; RP11-63K6.3
Gene Aliases: CASP8AP2; CED-4; FLASH; KIAA1315; RIP25
UniProt ID: (Human) Q9UKL3
Entrez Gene ID: (Human) 9994
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