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Invitrogen
Human FMNL3 (aa 413-538) Control Fragment Recombinant Protein
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Product Details
RP-102029
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
LDLENENMMRVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIKEKEEAFQRRCHLEPNVRGLESVDSEALARVGPAELSEGMPPSDLDLLAPAPPPEEVLPLPPPPAPPLPPPPPPLPDKCP
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
1M urea/PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (91%), Rat (91%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-54720. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
FMNL3, also known as Formin-like protein 3, is a 1028 amino acid containing protein involved in immunity or defense. This developmental protein is implicated in polarity control, invasion, migration, or metastasis through regulation of the Rho-related signaling pathway. It belongs to the formin homology family and contains a FH2 (formin homology 2) domain and a GBD/FH3 (Rho GTPase-binding/formin homology 3) domain and has high sequence identity to the mouse Wbp3 protein. Two different isoforms have been described. Itis suspectedbe involved in gastric cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Formin homology 2 domain-containing protein 3; formin-like 3; Formin-like protein 3; WBP-3; WW domain binding protein 3; WW domain-binding protein 3
Gene Aliases: FHOD3; FMNL3; FRL2; KIAA2014; WBP-3; WBP3
UniProt ID: (Human) Q8IVF7
Entrez Gene ID: (Human) 91010
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