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Invitrogen
Human FOXR1 (aa 146-284) Control Fragment Recombinant Protein
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Product Details
RP-109716
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
LPSPHKRAPLQSRRLRQASSQAGRLWSRPPLNYFHLIALALRNSSPCGLNVQQIYSFTRKHFPFFRTAPEGWKNTVRHNLCFRDSFEKVPVSMQGGASTRPRSCLWKLTEEGHRRFAEEARALASTRLESIQQCMSQPD
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
1M urea/PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (54%), Rat (54%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-144774. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
The forkhead-box (FOX) genes comprise a superfamily of at least 43 members that express proteins which are involved in transcriptional regulation and may be associated with the pathogenesis of various cancers. FOX family members are monomeric, helix-turn-helix proteins with a core DNA-binding domain of approximately 110 amino acids. FOX transcription factors play roles in determining cell fate during early development. FOXR1 (forkhead box protein R1), also known as FOXN5 (forkhead box protein N5) or DLNB13, is a 292 amino acid nuclear protein that belongs to the FOX family and contains one forkhead DNA-binding domain. Through chromosomal aberrations such as retroviral integration, gene amplification or translocation, FOXR1 may be involved the development of certain invasive carcinomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Forkhead box protein N5; Forkhead box protein R1; forkhead box R1 variant 1; forkhead box R1 variant 2
Gene Aliases: DLNB13; FOXN5; FOXR1
UniProt ID: (Human) Q6PIV2
Entrez Gene ID: (Human) 283150
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