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Invitrogen
Human FXR1 (aa 552-620) Control Fragment Recombinant Protein
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Product Details
RP-106639
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
NLPRETLAKNKKEMAKDVIEEHGPSEKAINGPTSASGDDISKLQRTPGEEKINTLKEENTQEAAVLNGV
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
1M urea/PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (88%), Rat (88%).
This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
FXR1 is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. It may regulate intracellular transport and local transltion of certain mRNAs. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. FXR1 is required for embryonic and postnatal development of muscle tissue. Three transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FMR1 autosomal homolog 1; fragile X mental retardation autosomal homolog variant p1K; fragile X mental retardation autosomal homolog variant p2K; fragile X mental retardation autosomal homolog variant p4K; fragile X mental retardation autosomal homolog variant p5FK; fragile X mental retardation, autosomal homolog 1; hFXR1p; RNA-binding protein FXR1
Gene Aliases: FXR1; FXR1P
UniProt ID: (Human) P51114
Entrez Gene ID: (Human) 8087
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