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Invitrogen
Human Fc gamma RIIB (CD32b) His-tag Recombinant Protein
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Product Details
A42520
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
HEK293 cells
Amino acid sequence
Human CD32b, amino acids Ala46-Pro217 (Accession # NP_001002274.1) with an N-terminal signal peptide and a C-terminal His-tag
Tag
His-tag
Molecular weight
20.8 kDa
Class
Recombinant
Type
Protein
Purity
≥95 % as determined by SDS-PAGE. ≥95 % as determined by SEC-HPLC.
Endotoxin concentration
<1.0 EU/µg
Activity
Measured by its ability to bind biotinylated human IgG2 in functional ELISA.
Conjugate
Form
Lyophilized
Purification
purified
Storage buffer
PBS, pH 7.4, with 5% mannitol, 5% trehalose, 0.01% Tween 80
Contains
no preservative
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient
Product Specific Information
Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2 mg/mL or lower. It is recommended that the protein be aliquoted and be used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.
Target Information
This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD32; CD32 receptor 2; CD32 receptor 2a; CD32 receptor 2b; CD32A; CDw32; Fc fragment of IgG, low affinity II, receptor for (CD32); Fc fragment of IgG, low affinity IIb, receptor (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32); Fc gamma receptor IIb; Fc gamma RIIb; fc-gamma RII-a; Fc-gamma RII-b; fc-gamma-RIIa; Fc-gamma-RIIb; FcGR; FCGR2A1; fcRII-a; fcRII-b; FGFR2B; IgG Fc receptor II-b; Low affinity immunoglobulin gamma Fc region receptor II-b
Gene Aliases: CD32; CD32B; FCG2; FCGR2; FCGR2B; IGFR2
UniProt ID: (Human) P31994
Entrez Gene ID: (Human) 2213
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