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Invitrogen
Human GPX2 (aa 1-38) Control Fragment Recombinant Protein
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Product Details
RP-110129
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
MAFIAKSFYDLSAISLDGEKVDFNTFRGRAVLIENVAS
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
1M urea/PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (89%), Rat (89%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-145089. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
This gene is a member of the glutathione peroxidase family and encodes a selenium-dependent glutathione peroxidase that is one of two isoenzymes responsible for the majority of the glutathione-dependent hydrogen peroxide-reducing activity in the epithelium of the gastrointestinal tract. Studies in knockout mice indicate that mRNA expression levels respond to luminal microflora, suggesting a role of the ileal glutathione peroxidases in preventing inflammation in the GI tract.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Gastrointestinal glutathione peroxidase; Glutathione peroxidase 2; glutathione peroxidase 2 (gastrointestinal); Glutathione peroxidase-gastrointestinal; Glutathione peroxidase-related protein 2; GPRP-2; GPx-2; GPx-GI; HGNC:4554; Phospholipid hydroperoxide glutathione peroxidase GPX2
Gene Aliases: GI-GPx; GPRP; GPRP-2; GPx-2; GPx-GI; GPX2; GSHPx-2; GSHPX-GI
UniProt ID: (Human) P18283
Entrez Gene ID: (Human) 2877
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