Invitrogen

Human GSG2 (aa 682-768) Control Fragment Recombinant Protein

Product Details

RP-95239

Applications

Tested Dilution

Publications

Control (Ctrl)

Assay-dependent

Blocking Assay (BLOCK)

Assay-dependent

Product Specifications

Species

Human

Expression System

E. coli

Amino acid sequence

QVSIIDYTLSRLERDGIVVFCDVSMDEDLFTGDGDYQFDIYRLMKKENNNRWGEYHPYSNVLWLHYLTDKMLKQMTFKTKCNTPAMK

Tag

His-ABP-tag

Class

Recombinant

Type

Protein

Purity

>80% by SDS-PAGE and Coomassie blue staining

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

≥5.0 mg/mL

Purification

purified

Storage buffer

PBS/1M urea, pH 7.4

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Product Specific Information

Highest antigen sequence indentity to the following orthologs: Mouse (80%), Rat (80%).

This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-55608. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Target Information

GSG2 (haspin) is a conserved kinase required for mitosis. GSG2 phosphorylates histone H3 and is viewed as a potential therapeutic target for oncology. GSG2 is required for normal alignment of chromosomes at metaphase.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: germ cell associated 2 (haspin); Germ cell-specific gene 2 protein; H-haspin; Haploid germ cell-specific nuclear protein kinase; Serine/threonine-protein kinase haspin