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Invitrogen
Human HOXD13 (aa 191-261) Control Fragment Recombinant Protein
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Product Details
RP-107309
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
SFYQGYTSPYQHVPGYIDMVSTFGSGEPRHEAYISMEGYQSWTLANGWNSQVYCTKDQPQGSHFWKSSFPG
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (99%), Rat (99%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-66661. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
HOXD13 (homeobox protein D13) belongs to a class of transcription factors called homeobox proteins. In vertebrates, homeobox are found in clusters called A, B, C, and D on four separate chromosomes. Expression of homeobox proteins is spatially and temporally regulated during embryonic development. The gene encoding HOXD13 is part of the D cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. Mutations in the HOXD13 gene cause synpolydactyly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: homeo box 4I; homeo box D13; Homeobox protein Hox-4I; Homeobox protein Hox-D13
Gene Aliases: BDE; BDSD; HOX4I; HOXD13; SPD; SPD1
UniProt ID: (Human) P35453
Entrez Gene ID: (Human) 3239
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