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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (79%), Rat (79%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-51393. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene functions as a cofactor for the stimulation of transcriptional elongation by HIV-1 Tat, which binds to the HIV-1 promoter through Tat-TAR interaction. This protein may also serve as a dual-function factor to couple transcription and splicing and to facilitate their reciprocal activation. Alternatively spliced transcript variants have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 17S U2 SnRNP complex component HTATSF1; cofactor required for Tat activation of HIV-1 transcription; HIV TAT specific factor 1; HIV Tat-specific factor 1; RP1-196E23.2; Tat-SF1
Gene Aliases: dJ196E23.2; HTATSF1; TAT-SF1; TATSF1
UniProt ID: (Human) O43719
Entrez Gene ID: (Human) 27336
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