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Product Details
200-35-20UG
Applications
Tested Dilution
Publications
Product Specifications
Published species
Human
Expression System
CHO cells
Class
Recombinant
Type
Protein
Conjugate
Storage conditions
-20°C
Shipping conditions
Ambient
Product Specific Information
200-35-1MG will be provided as 2 x 500 µg (200-35-500UG).
Recombinant Human IL-24 is an 18.9 kDa glycoprotein that contains 161 amino acid residues, including a C-terminal His-tag.
This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
Target Information
Interleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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