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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (95%), Rat (95%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-65562. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
IRF2BP1 acts as a transcriptional repressor. IRF2BP1 also acts as a transcriptional corepressor in a IRF2-dependent manner. This repression is not mediated at least in part by histone deacetylase activities.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DKFZP434M154; Interferon regulatory factor 2-binding protein 1; IRF-2-binding protein 1; Probable E3 ubiquitin-protein ligase IRF2BP1; Probable RING-type E3 ubiquitin transferase IRF2BP1
Gene Aliases: IRF2BP1
UniProt ID: (Human) Q8IU81
Entrez Gene ID: (Human) 26145
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