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Invitrogen
Human ITGB1BP3 (aa 168-230) Control Fragment Recombinant Protein
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Product Details
RP-106571
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
VYLDGMKSREELFREVLEDIQNSLLNRSQESAPSPARPARTQGPGRGCGHRTARPAASQQDSM
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
1M urea/PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (35%), Rat (35%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibodies, PA5-65897, PA5-67242. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
ITGB1BP3 catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). The protein reduces laminin matrix deposition and cell adhesion to laminin, but not to fibronectin. It is involved in the regulation of PXN at the protein level and of PXN tyrosine phosphorylation and may play a role in the regulation of terminal myogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Integrin beta-1-binding protein 3; MIBP; Muscle integrin-binding protein; muscle-specific beta 1 integrin binding protein; Nicotinamide riboside kinase 2; Nicotinic acid riboside kinase 2; nmR-K 2; NRK 2; Ribosylnicotinamide kinase 2; Ribosylnicotinic acid kinase 2; RNK 2
Gene Aliases: ITGB1BP3; MIBP; NMRK2; NRK2
UniProt ID: (Human) Q9NPI5
Entrez Gene ID: (Human) 27231
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