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Invitrogen
Human JWA (aa 129-188) Control Fragment Recombinant Protein
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Product Details
RP-91079
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
PLLLMFIHASLRLRNLKNKLENKMEGIGLKRTPMGIVLDALEQQEEGINRLTDYISKVKE
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (85%), Rat (85%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-53319. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
JWA protein expression is affected by vitamin A and may be associated with the cytoskeleton. A protein similar to JWA in rats may play a role in the regulation of cell differentiation by inhibiting the cell membrane glutamate transporter EAAC1. The expression of the rat gene is upregulated by retinoic acid, which results in a specific reduction in EAAC1-mediated glutamate transport.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ADP-ribosylation factor GTPase 6 interacting protein 5; ADP-ribosylation factor like GTPase 6 interacting protein 5; ADP-ribosylation factor-like 6 interacting protein 5; ADP-ribosylation factor-like protein 6-interacting protein 5; ADP-ribosylation-like factor 6 interacting protein 5; aip-5; ARL-6-interacting protein 5; cytoskeleton related vitamin A responsive protein; Cytoskeleton-related vitamin A-responsive protein; dermal papilla derived protein 11; Dermal papilla-derived protein 11; Glutamate transporter EAAC1-interacting protein; glutamate transporter EEAC1-associated protein; GTRAP3-18; JM5; PRA1 domain family 3; PRA1 family protein 3; Prenylated Rab acceptor protein 2; Protein JWa; putative MAPK activating protein PM27; Putative MAPK-activating protein PM27
Gene Aliases: addicsin; ARL6IP5; DERP11; GTRAP3-18; hp22; HSPC127; jmx; JWA; PRA2; PRAF3; Yip6b
UniProt ID: (Human) O75915
Entrez Gene ID: (Human) 10550
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