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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (72%), Rat (72%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-53713. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. There are at least two alternatively spliced transcript variants derived from this gene and encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: eag-related protein 3; ERG-3; Ether-a-go-go-related gene potassium channel 3; ether-a-go-go-related protein 3; H Kv11.3; potassium channel subunit HERG-3; potassium channel, voltage gated eag related subfamily H, member 7; Potassium voltage-gated channel subfamily H member 7; Voltage-gated inwardly rectifying potassium channel KCNH7; Voltage-gated potassium channel subunit Kv11.3
Gene Aliases: ERG3; HERG3; KCNH7; Kv11.3
UniProt ID: (Human) Q9NS40
Entrez Gene ID: (Human) 90134
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