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Highest antigen sequence indentity to the following orthologs: Mouse (34%), Rat (34%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-60543. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. This gene is activated at alkaline pH. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 2P domain potassium channel Talk-2; Acid-sensitive potassium channel protein TASK-4; Potassium channel subfamily K member 17; potassium channel, two pore domain subfamily K, member 17; TALK-2; TWIK-related acid-sensitive K(+) channel 4; TWIK-related alkaline pH-activated K(+) channel 2
Gene Aliases: K2p17.1; KCNK17; TALK-2; TALK2; TASK-4; TASK4; UNQ5816/PRO19634
UniProt ID: (Human) Q96T54
Entrez Gene ID: (Human) 89822
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