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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (68%), Rat (68%).
This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: glandular kallikrein 1; kallikrein 1, renal/pancreas/salivary; kallikrein serine protease 1; Kallikrein-1; Kidney/pancreas/salivary gland kallikrein; Tissue kallikrein
Gene Aliases: hK1; KLK1; Klk6; KLKR
UniProt ID: (Human) P06870
Entrez Gene ID: (Human) 3816
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