Product References
Initial Characterization of 3D Culture of Yolk Sac Tissue.
Animals : an open access journal from MDPI
Pereira VM,Pinto PAF,Motta LCB,Almeida MF,de Andrade AFC,Pavaneli APP,Ambrósio CE
300-05 was used in Cell Culture to standardise 3D culture techniques for the yolk sac in three domestic species (porcine, canine, and bovine) models.
Sat Apr 22 00:00:00 UTC 2023
Derivation and Primordial Germ Cell Induction of Intermediate Pluripotent Stem Cells.
Methods in molecular biology (Clifton, N.J.)
Yu L,Ballard E,Pinzon Arteaga CA,Wu J
300-05 was used in In vitro experiments to describe the method for derivation and maintenance of mouse and human FTW-PSCs, as well as PGC-LC induction from FTW-PSCs.
Fri Jul 21 00:00:00 UTC 2023
Dissecting peri-implantation development using cultured human embryos and embryo-like assembloids.
Cell research
Ai Z,Niu B,Yin Y,Xiang L,Shi G,Duan K,Wang S,Hu Y,Zhang C,Zhang C,Rong L,Kong R,Chen T,Guo Y,Liu W,Li N,Zhao S,Zhu X,Mai X,Li Y,Wu Z,Zheng Y,Fu J,Ji W,Li T
300-05 was used in Cell Culture to provide insights into human peri-implantation development, and the E-assembloid offers a useful model to disentangle cellular behaviors and signaling interactions that drive human embryogenesis.
Fri Sep 01 00:00:00 UTC 2023
Derivation of Arbas Cashmere Goat Induced Pluripotent Stem Cells in LCDM with Trophectoderm Lineage Differentiation and Interspecies Chimeric Abilities.
International journal of molecular sciences
Liu F,Wang J,Yue Y,Li C,Zhang X,Xiang J,Wang H,Li X
300-05 was used in Cell Culture to apply LCDM to generate goat induced pluripotent stem cells (giPSCs) from goat fetal fibroblasts (GFFs) by reprogramming.
Fri Sep 29 00:00:00 UTC 2023
Tex10 interacts with STAT3 to regulate hepatocellular carcinoma growth and metastasis.
Molecular carcinogenesis
Xiang X,Kuang W,Yu C,Li Y,Su Q,Tian Y,Li J
300-05 was used in Cell Culture to indicate that Tex10 functions as an oncogene by upregulating STAT3 activity, thus suggesting that Tex10 may serve as a prognostic biomarker and/or therapeutic target for HCC patients.
Fri Dec 01 00:00:00 UTC 2023
A human proteogenomic-cellular framework identifies KIF5A as a modulator of astrocyte process integrity with relevance to ALS.
Communications biology
Szebényi K,Barrio-Hernandez I,Gibbons GM,Biasetti L,Troakes C,Beltrao P,Lakatos A
300-05 was used in Cell Culture to show that this may underly cytoskeletal and trafficking changes in SOD1 ALS astrocytes characterised by low KIF5A levels, which can be rescued by c-Jun N-terminal Kinase-1 (JNK1), a kinesin transport regulator.
Thu Jun 29 00:00:00 UTC 2023
Proteomic Analysis of Huntington's Disease Medium Spiny Neurons Identifies Alterations in Lipid Droplets.
Molecular & cellular proteomics : MCP
Tshilenge KT,Aguirre CG,Bons J,Gerencser AA,Basisty N,Song S,Rose J,Lopez-Ramirez A,Naphade S,Loureiro A,Battistoni E,Milani M,Wehrfritz C,Holtz A,Hetz C,Mooney SD,Schilling B,Ellerby LM
300-05 was used in Cell Culture to define the proteome of human Huntington's disease patient-derived medium-spiny projection neurons.
Mon May 01 00:00:00 UTC 2023
Generation and characterization of stable pig pregastrulation epiblast stem cell lines.
Cell research
Zhi M,Zhang J,Tang Q,Yu D,Gao S,Gao D,Liu P,Guo J,Hai T,Gao J,Cao S,Zhao Z,Li C,Weng X,He M,Chen T,Wang Y,Long K,Jiao D,Li G,Zhang J,Liu Y,Lin Y,Pang D,Zhu Q,Chen N,Huang J,Chen X,Yao Y,Yang J,Xie Z,Huang X,Liu M,Zhang R,Li Q,Miao Y,Tian J,Huang X,Ouyang H,Liu B,Xie W,Zhou Q,Wei H,Liu Z,Zheng C,Li M,Han J
Fri Apr 01 00:00:00 UTC 2022
Generation of mitochondria-rich kidney organoids from expandable intermediate mesoderm progenitors reprogrammed from human urine cells under defined medium.
Cell & bioscience
Yuan Y,Chen H,Ou S,Cai B,Zhang R,Qin Y,Pan M,Cao S,Pei D,Hou FF
300-05 was used in Cell Culture to evaluate the use of reprogramming mitochondria-rich hUCs to generate mitochondria-rich kidney organoids.
Sat Oct 15 00:00:00 UTC 2022
Stem-cell-derived trophoblast organoids model human placental development and susceptibility to emerging pathogens.
Cell stem cell
Karvas RM,Khan SA,Verma S,Yin Y,Kulkarni D,Dong C,Park KM,Chew B,Sane E,Fischer LA,Kumar D,Ma L,Boon ACM,Dietmann S,Mysorekar IU,Theunissen TW
300-05 was used in Cell Culture to demonstrate that SC-TOs exhibit selective vulnerability to emerging pathogens (SARS-CoV-2 and Zika virus), which correlates with expression levels of their respective entry factors.
Thu May 05 00:00:00 UTC 2022
Streamlined and quantitative detection of chimerism using digital PCR.
Scientific reports
Suchy FP,Nishimura T,Seki S,Wilkinson AC,Higuchi M,Hsu I,Zhang J,Bhadury J,Nakauchi H
300-05 was used in Cell Culture to develop a droplet digital PCR single-nucleotide discrimination assay which can detect chimerism among common albino and non-albino mouse strains and to streamline sample preparation by validating that the assay is compatible with crude lysate from all solid organs.
Fri Jun 17 00:00:00 UTC 2022
Interactions between cancer cells and immune cells drive transitions to mesenchymal-like states in glioblastoma.
Cancer cell
Hara T,Chanoch-Myers R,Mathewson ND,Myskiw C,Atta L,Bussema L,Eichhorn SW,Greenwald AC,Kinker GS,Rodman C,Gonzalez Castro LN,Wakimoto H,Rozenblatt-Rosen O,Zhuang X,Fan J,Hunter T,Verma IM,Wucherpfennig KW,Regev A,Suvà ML,Tirosh I
Mon Jun 14 00:00:00 UTC 2021
H3.3-K27M drives neural stem cell-specific gliomagenesis in a human iPSC-derived model.
Cancer cell
Haag D,Mack N,Benites Goncalves da Silva P,Statz B,Clark J,Tanabe K,Sharma T,Jäger N,Jones DTW,Kawauchi D,Wernig M,Pfister SM
Mon Mar 08 00:00:00 UTC 2021
Principles of signaling pathway modulation for enhancing human naive pluripotency induction.
Cell stem cell
Bayerl J,Ayyash M,Shani T,Manor YS,Gafni O,Massarwa R,Kalma Y,Aguilera-Castrejon A,Zerbib M,Amir H,Sheban D,Geula S,Mor N,Weinberger L,Naveh Tassa S,Krupalnik V,Oldak B,Livnat N,Tarazi S,Tawil S,Wildschutz E,Ashouokhi S,Lasman L,Rotter V,Hanna S,Ben-Yosef D,Novershtern N,Viukov S,Hanna JH
Thu Sep 02 00:00:00 UTC 2021
Activin A-derived human embryonic stem cells show increased competence to differentiate into primordial germ cell-like cells.
Stem cells (Dayton, Ohio)
Mishra S,Taelman J,Popovic M,Tilleman L,Duthoo E,van der Jeught M,Deforce D,van Nieuwerburgh F,Menten B,de Sutter P,Boel A,Chuva De Sousa Lopes SM,Heindryckx B
Sat May 01 00:00:00 UTC 2021
Tracing the emergence of primordial germ cells from bilaminar disc rabbit embryos and pluripotent stem cells.
Cell reports
Kobayashi T,Castillo-Venzor A,Penfold CA,Morgan M,Mizuno N,Tang WWC,Osada Y,Hirao M,Yoshida F,Sato H,Nakauchi H,Hirabayashi M,Surani MA
Tue Oct 12 00:00:00 UTC 2021
Reconstructing aspects of human embryogenesis with pluripotent stem cells.
Nature communications
Sozen B,Jorgensen V,Weatherbee BAT,Chen S,Zhu M,Zernicka-Goetz M
Tue Sep 21 00:00:00 UTC 2021
OCT4 cooperates with distinct ATP-dependent chromatin remodelers in naïve and primed pluripotent states in human.
Nature communications
Huang X,Park KM,Gontarz P,Zhang B,Pan J,McKenzie Z,Fischer LA,Dong C,Dietmann S,Xing X,Shliaha PV,Yang J,Li D,Ding J,Lungjangwa T,Mitalipova M,Khan SA,Imsoonthornruksa S,Jensen N,Wang T,Kadoch C,Jaenisch R,Wang J,Theunissen TW
Thu Aug 26 00:00:00 UTC 2021
BASP1 labels neural stem cells in the neurogenic niches of mammalian brain.
Scientific reports
Manganas LN,Durá I,Osenberg S,Semerci F,Tosun M,Mishra R,Parkitny L,Encinas JM,Maletic-Savatic M
Wed Mar 10 00:00:00 UTC 2021
Unbiased identification of novel transcription factors in striatal compartmentation and striosome maturation.
eLife
Cirnaru MD,Song S,Tshilenge KT,Corwin C,Mleczko J,Galicia Aguirre C,Benlhabib H,Bendl J,Apontes P,Fullard J,Creus-Muncunill J,Reyahi A,Nik AM,Carlsson P,Roussos P,Mooney SD,Ellerby LM,Ehrlich ME
300-05 was used in Cell Culture to dissect and manipulate the transcription factor networks regulating medium spiny neurone compartmentation and differentiation,.
Tue Oct 05 00:00:00 UTC 2021
Probing the signaling requirements for naive human pluripotency by high-throughput chemical screening.
Cell reports
Khan SA,Park KM,Fischer LA,Dong C,Lungjangwa T,Jimenez M,Casalena D,Chew B,Dietmann S,Auld DS,Jaenisch R,Theunissen TW
Tue Jun 15 00:00:00 UTC 2021
Origins and Proliferative States of Human Oligodendrocyte Precursor Cells.
Cell
Huang W,Bhaduri A,Velmeshev D,Wang S,Wang L,Rottkamp CA,Alvarez-Buylla A,Rowitch DH,Kriegstein AR
300-05 was used in Cell Culture to indicate properties of OPC derivation, proliferation, and dispersion important for human white matter expansion and myelination.
Thu Aug 06 00:00:00 UTC 2020
Metabolic switch and epithelial-mesenchymal transition cooperate to regulate pluripotency.
The EMBO journal
Sun H,Yang X,Liang L,Zhang M,Li Y,Chen J,Wang F,Yang T,Meng F,Lai X,Li C,He J,He M,Xu Q,Li Q,Lin L,Pei D,Zheng H
Wed Apr 15 00:00:00 UTC 2020
A variant in IL6ST with a selective IL-11 signaling defect in human and mouse.
Bone research
Schwerd T,Krause F,Twigg SRF,Aschenbrenner D,Chen YH,Borgmeyer U,Müller M,Manrique S,Schumacher N,Wall SA,Jung J,Damm T,Glüer CC,Scheller J,Rose-John S,Jones EY,Laurence A,Wilkie AOM,Schmidt-Arras D,Uhlig HH
Wed Mar 06 00:00:00 UTC 2024
Effective Inhibition of MYC-Amplified Group 3 Medulloblastoma Through Targeting EIF4A1.
Cancer management and research
Zhao Y,Li T,Tian S,Meng W,Sui Y,Yang J,Wang B,Liang Z,Zhao H,Han Y,Tang Y,Zhang L,Ma J
300-05 was used in Cell Culture to study the identification of novel effective therapeutic strategies against MYC-amplified group 3 (G3)-medulloblastoma (MB) via targeting MYC translation to show that interrupting MYC translation by EIF4A1 inhibition could be a potential effective therapeutic approach when treating patients with MYC-amplified G3-MB.
Mon Apr 18 00:00:00 UTC 2022
Regulation of cytokine signaling through direct interaction between cytokine receptors and the ATG16L1 WD40 domain.
Nature communications
Serramito-Gómez I,Boada-Romero E,Villamuera R,Fernández-Cabrera Á,Cedillo JL,Martín-Regalado Á,Carding S,Mayer U,Powell PP,Wileman T,García-Higuera I,Pimentel-Muiños FX
Fri Nov 20 00:00:00 UTC 2020
Vascular progenitors generated from tankyrase inhibitor-regulated naïve diabetic human iPSC potentiate efficient revascularization of ischemic retina.
Nature communications
Park TS,Zimmerlin L,Evans-Moses R,Thomas J,Huo JS,Kanherkar R,He A,Ruzgar N,Grebe R,Bhutto I,Barbato M,Koldobskiy MA,Lutty G,Zambidis ET
Thu Mar 05 00:00:00 UTC 2020
Raman image-activated cell sorting.
Nature communications
Nitta N,Iino T,Isozaki A,Yamagishi M,Kitahama Y,Sakuma S,Suzuki Y,Tezuka H,Oikawa M,Arai F,Asai T,Deng D,Fukuzawa H,Hase M,Hasunuma T,Hayakawa T,Hiraki K,Hiramatsu K,Hoshino Y,Inaba M,Inoue Y,Ito T,Kajikawa M,Karakawa H,Kasai Y,Kato Y,Kobayashi H,Lei C,Matsusaka S,Mikami H,Nakagawa A,Numata K,Ota T,Sekiya T,Shiba K,Shirasaki Y,Suzuki N,Tanaka S,Ueno S,Watarai H,Yamano T,Yazawa M,Yonamine Y,Di Carlo D,Hosokawa Y,Uemura S,Sugimura T,Ozeki Y,Goda K
Fri Jul 10 00:00:00 UTC 2020
Fiber reinforced GelMA hydrogel to induce the regeneration of corneal stroma.
Nature communications
Kong B,Chen Y,Liu R,Liu X,Liu C,Shao Z,Xiong L,Liu X,Sun W,Mi S
Wed Mar 18 00:00:00 UTC 2020
High-Resolution Dissection of Chemical Reprogramming from Mouse Embryonic Fibroblasts into Fibrocartilaginous Cells.
Stem cell reports
Chen Y,Wu B,Lin J,Yu D,Du X,Sheng Z,Yu Y,An C,Zhang X,Li Q,Zhu S,Sun H,Zhang X,Zhang S,Zhou J,Bunpetch V,El-Hashash A,Ji J,Ouyang H
Tue Mar 10 00:00:00 UTC 2020
Transition to naïve human pluripotency mirrors pan-cancer DNA hypermethylation.
Nature communications
Patani H,Rushton MD,Higham J,Teijeiro SA,Oxley D,Cutillas P,Sproul D,Ficz G
Wed Jul 22 00:00:00 UTC 2020
Zika Virus with Increased CpG Dinucleotide Frequencies Shows Oncolytic Activity in Glioblastoma Stem Cells.
Viruses
Trus I,Berube N,Jiang P,Rak J,Gerdts V,Karniychuk U
300-05 was used in Cell Culture to study whether cytosine phosphate-guanine (CpG) recoding in a viral genome may provide oncolytic candidates with reduced infection kinetics in nonmalignant brain cells, but with high virulence in glioblastoma stem cells (GSCs).
Mon May 25 00:00:00 UTC 2020
Generation of Blastocyst-like Structures from Mouse Embryonic and Adult Cell Cultures.
Cell
Li R,Zhong C,Yu Y,Liu H,Sakurai M,Yu L,Min Z,Shi L,Wei Y,Takahashi Y,Liao HK,Qiao J,Deng H,Nuñez-Delicado E,Rodriguez Esteban C,Wu J,Izpisua Belmonte JC
Thu Oct 17 00:00:00 UTC 2019
Deciphering the "m6A Code" via Antibody-Independent Quantitative Profiling.
Cell
Garcia-Campos MA,Edelheit S,Toth U,Safra M,Shachar R,Viukov S,Winkler R,Nir R,Lasman L,Brandis A,Hanna JH,Rossmanith W,Schwartz S
Thu Jul 25 00:00:00 UTC 2019
Efficient exogenous DNA-free reprogramming with suicide gene vectors.
Experimental & molecular medicine
Lee M,Ha J,Son YS,Ahn H,Jung KB,Son MY,Kim J
Fri Jul 19 00:00:00 UTC 2019
A Chemically Defined Feeder-free System for the Establishment and Maintenance of the Human Naive Pluripotent State.
Stem cell reports
Szczerbinska I,Gonzales KAU,Cukuroglu E,Ramli MNB,Lee BPG,Tan CP,Wong CK,Rancati GI,Liang H,Göke J,Ng HH,Chan YS
Tue Oct 08 00:00:00 UTC 2019
A dose-dependent response to MEK inhibition determines hypoblast fate in bovine embryos.
BMC developmental biology
Canizo JR,Ynsaurralde Rivolta AE,Vazquez Echegaray C,Suvá M,Alberio V,Aller JF,Guberman AS,Salamone DF,Alberio RH,Alberio R
300-05 was used in Cell Culture to show that SOX17 can be used as a reliable early marker of hypoblast in the bovine, and based on its expression profile we show that the hypoblast segregates in day 7 blastocysts.
Thu Jul 04 00:00:00 UTC 2019
Self-Organization of Mouse Stem Cells into an Extended Potential Blastoid.
Developmental cell
Sozen B,Cox AL,De Jonghe J,Bao M,Hollfelder F,Glover DM,Zernicka-Goetz M
300-05 was used in Cell Culture to show that mouse embryonic stem cells cultured under extended pluripotent conditions (EPSCs) can be partnered with trophoblast stem cells to self-organize into blastocyst-like structures with all three embryonic and extra-embryonic lineages.
Mon Dec 16 00:00:00 UTC 2019
Chromatin analysis in human early development reveals epigenetic transition during ZGA.
Nature
Wu J,Xu J,Liu B,Yao G,Wang P,Lin Z,Huang B,Wang X,Li T,Shi S,Zhang N,Duan F,Ming J,Zhang X,Niu W,Song W,Jin H,Guo Y,Dai S,Hu L,Fang L,Wang Q,Li Y,Li W,Na J,Xie W,Sun Y
Tue May 01 00:00:00 UTC 2018
Reduced MEK inhibition preserves genomic stability in naive human embryonic stem cells.
Nature methods
Di Stefano B,Ueda M,Sabri S,Brumbaugh J,Huebner AJ,Sahakyan A,Clement K,Clowers KJ,Erickson AR,Shioda K,Gygi SP,Gu H,Shioda T,Meissner A,Takashima Y,Plath K,Hochedlinger K
Sat Sep 01 00:00:00 UTC 2018
Generation and post-injury integration of human spinal cord neural stem cells.
Nature methods
Kumamaru H,Kadoya K,Adler AF,Takashima Y,Graham L,Coppola G,Tuszynski MH
Sat Sep 01 00:00:00 UTC 2018
Human Induced Pluripotent Stem Cell-Derived Astrocytes Are Differentially Activated by Multiple Sclerosis-Associated Cytokines.
Stem cell reports
Perriot S,Mathias A,Perriard G,Canales M,Jonkmans N,Merienne N,Meunier C,El Kassar L,Perrier AL,Laplaud DA,Schluep M,Déglon N,Du Pasquier R
Tue Nov 13 00:00:00 UTC 2018
MTCH2-mediated mitochondrial fusion drives exit from naïve pluripotency in embryonic stem cells.
Nature communications
Bahat A,Goldman A,Zaltsman Y,Khan DH,Halperin C,Amzallag E,Krupalnik V,Mullokandov M,Silberman A,Erez A,Schimmer AD,Hanna JH,Gross A
Mon Dec 03 00:00:00 UTC 2018
Unique molecular events during reprogramming of human somatic cells to induced pluripotent stem cells (iPSCs) at naïve state.
eLife
Wang Y,Zhao C,Hou Z,Yang Y,Bi Y,Wang H,Zhang Y,Gao S
300-05 was used in Cell Culture to conclude that dissecting the naïve reprogramming dynamics by integrative analysis improves the understanding of the molecular features involved in the generation of naïve pluripotency directly from somatic cells.
Tue Jan 30 00:00:00 UTC 2018
Allele-specific repression of Sox2 through the long non-coding RNA Sox2ot.
Scientific reports
Messemaker TC,van Leeuwen SM,van den Berg PR,'t Jong AEJ,Palstra RJ,Hoeben RC,Semrau S,Mikkers HMM
Wed Jan 10 00:00:00 UTC 2018
Pluripotent state transitions coordinate morphogenesis in mouse and human embryos.
Nature
Shahbazi MN,Scialdone A,Skorupska N,Weberling A,Recher G,Zhu M,Jedrusik A,Devito LG,Noli L,Macaulay IC,Buecker C,Khalaf Y,Ilic D,Voet T,Marioni JC,Zernicka-Goetz M
Thu Dec 14 00:00:00 UTC 2017
Interspecies Chimerism with Mammalian Pluripotent Stem Cells.
Cell
Wu J,Platero-Luengo A,Sakurai M,Sugawara A,Gil MA,Yamauchi T,Suzuki K,Bogliotti YS,Cuello C,Morales Valencia M,Okumura D,Luo J,Vilariño M,Parrilla I,Soto DA,Martinez CA,Hishida T,Sánchez-Bautista S,Martinez-Martinez ML,Wang H,Nohalez A,Aizawa E,Martinez-Redondo P,Ocampo A,Reddy P,Roca J,Maga EA,Esteban CR,Berggren WT,Nuñez Delicado E,Lajara J,Guillen I,Guillen P,Campistol JM,Martinez EA,Ross PJ,Izpisua Belmonte JC
Thu Jan 26 00:00:00 UTC 2017
Interspecies Chimerism with Mammalian Pluripotent Stem Cells.
Cell
Wu J,Platero-Luengo A,Sakurai M,Sugawara A,Gil MA,Yamauchi T,Suzuki K,Bogliotti YS,Cuello C,Morales Valencia M,Okumura D,Luo J,Vilariño M,Parrilla I,Soto DA,Martinez CA,Hishida T,Sánchez-Bautista S,Martinez-Martinez ML,Wang H,Nohalez A,Aizawa E,Martinez-Redondo P,Ocampo A,Reddy P,Roca J,Maga EA,Esteban CR,Berggren WT,Nuñez Delicado E,Lajara J,Guillen I,Guillen P,Campistol JM,Martinez EA,Ross PJ,Izpisua Belmonte JC
Thu Jan 26 00:00:00 UTC 2017
Interspecies Chimerism with Mammalian Pluripotent Stem Cells.
Cell
Wu J,Platero-Luengo A,Sakurai M,Sugawara A,Gil MA,Yamauchi T,Suzuki K,Bogliotti YS,Cuello C,Morales Valencia M,Okumura D,Luo J,Vilariño M,Parrilla I,Soto DA,Martinez CA,Hishida T,Sánchez-Bautista S,Martinez-Martinez ML,Wang H,Nohalez A,Aizawa E,Martinez-Redondo P,Ocampo A,Reddy P,Roca J,Maga EA,Esteban CR,Berggren WT,Nuñez Delicado E,Lajara J,Guillen I,Guillen P,Campistol JM,Martinez EA,Ross PJ,Izpisua Belmonte JC
Thu Jan 26 00:00:00 UTC 2017
Derivation of Pluripotent Stem Cells with In Vivo Embryonic and Extraembryonic Potency.
Cell
Yang Y,Liu B,Xu J,Wang J,Wu J,Shi C,Xu Y,Dong J,Wang C,Lai W,Zhu J,Xiong L,Zhu D,Li X,Yang W,Yamauchi T,Sugawara A,Li Z,Sun F,Li X,Li C,He A,Du Y,Wang T,Zhao C,Li H,Chi X,Zhang H,Liu Y,Li C,Duo S,Yin M,Shen H,Belmonte JCI,Deng H
Thu Apr 06 00:00:00 UTC 2017
Derivation of Pluripotent Stem Cells with In Vivo Embryonic and Extraembryonic Potency.
Cell
Yang Y,Liu B,Xu J,Wang J,Wu J,Shi C,Xu Y,Dong J,Wang C,Lai W,Zhu J,Xiong L,Zhu D,Li X,Yang W,Yamauchi T,Sugawara A,Li Z,Sun F,Li X,Li C,He A,Du Y,Wang T,Zhao C,Li H,Chi X,Zhang H,Liu Y,Li C,Duo S,Yin M,Shen H,Belmonte JCI,Deng H
Thu Apr 06 00:00:00 UTC 2017
JAK2-binding long noncoding RNA promotes breast cancer brain metastasis.
The Journal of clinical investigation
Wang S,Liang K,Hu Q,Li P,Song J,Yang Y,Yao J,Mangala LS,Li C,Yang W,Park PK,Hawke DH,Zhou J,Zhou Y,Xia W,Hung MC,Marks JR,Gallick GE,Lopez-Berestein G,Flores ER,Sood AK,Huang S,Yu D,Yang L,Lin C
Fri Dec 01 00:00:00 UTC 2017
JAK2-binding long noncoding RNA promotes breast cancer brain metastasis.
The Journal of clinical investigation
Wang S,Liang K,Hu Q,Li P,Song J,Yang Y,Yao J,Mangala LS,Li C,Yang W,Park PK,Hawke DH,Zhou J,Zhou Y,Xia W,Hung MC,Marks JR,Gallick GE,Lopez-Berestein G,Flores ER,Sood AK,Huang S,Yu D,Yang L,Lin C
Fri Dec 01 00:00:00 UTC 2017
A biallelic mutation in IL6ST encoding the GP130 co-receptor causes immunodeficiency and craniosynostosis.
The Journal of experimental medicine
Schwerd T,Twigg SRF,Aschenbrenner D,Manrique S,Miller KA,Taylor IB,Capitani M,McGowan SJ,Sweeney E,Weber A,Chen L,Bowness P,Riordan A,Cant A,Freeman AF,Milner JD,Holland SM,Frede N,Müller M,Schmidt-Arras D,Grimbacher B,Wall SA,Jones EY,Wilkie AOM,Uhlig HH
Mon Sep 04 00:00:00 UTC 2017
Differential expression of miR16 in glioblastoma and glioblastoma stem cells: their correlation with proliferation, differentiation, metastasis and prognosis.
Oncogene
Tian R,Wang J,Yan H,Wu J,Xu Q,Zhan X,Gui Z,Ding M,He J
Thu Oct 19 00:00:00 UTC 2017
Oncostatin M promotes cancer cell plasticity through cooperative STAT3-SMAD3 signaling.
Oncogene
Junk DJ,Bryson BL,Smigiel JM,Parameswaran N,Bartel CA,Jackson MW
300-05 was used in In vitro experiments to study the specific tumor microenvironment (TME) which most actively control cancer cell plasticity for metastasis.
Thu Jul 13 00:00:00 UTC 2017
SOX2 is required to maintain cancer stem cells in ovarian cancer.
Cancer science
Wen Y,Hou Y,Huang Z,Cai J,Wang Z
Sat Apr 01 00:00:00 UTC 2017
Altered Expression of Matrix Metalloproteinases and Their Endogenous Inhibitors in a Human Isogenic Stem Cell Model of Huntington's Disease.
Frontiers in neuroscience
Naphade S,Embusch A,Madushani KL,Ring KL,Ellerby LM
300-05 was used in Cell Culture to investigate matrix metalloproteases in Huntington’s Disease.
Wed Sep 30 00:00:00 UTC 2020
Novel STAT binding elements mediate IL-6 regulation of MMP-1 and MMP-3.
Scientific reports
Cutler SJ,Doecke JD,Ghazawi I,Yang J,Griffiths LR,Spring KJ,Ralph SJ,Mellick AS
Thu Aug 17 00:00:00 UTC 2017
Early reprogramming regulators identified by prospective isolation and mass cytometry.
Nature
Lujan E,Zunder ER,Ng YH,Goronzy IN,Nolan GP,Wernig M
Thu May 21 00:00:00 UTC 2015
Structure-based discovery of NANOG variant with enhanced properties to promote self-renewal and reprogramming of pluripotent stem cells.
Proceedings of the National Academy of Sciences of the United States of America
Hayashi Y,Caboni L,Das D,Yumoto F,Clayton T,Deller MC,Nguyen P,Farr CL,Chiu HJ,Miller MD,Elsliger MA,Deacon AM,Godzik A,Lesley SA,Tomoda K,Conklin BR,Wilson IA,Yamanaka S,Fletterick RJ
Tue Apr 14 00:00:00 UTC 2015
Brain vascular pericytes following ischemia have multipotential stem cell activity to differentiate into neural and vascular lineage cells.
Stem cells (Dayton, Ohio)
Nakagomi T,Kubo S,Nakano-Doi A,Sakuma R,Lu S,Narita A,Kawahara M,Taguchi A,Matsuyama T
Mon Jun 01 00:00:00 UTC 2015
Critical functions of RhoB in support of glioblastoma tumorigenesis.
Neuro-oncology
Ma Y,Gong Y,Cheng Z,Loganathan S,Kao C,Sarkaria JN,Abel TW,Wang J
300-05 was used in In vitro experiments to suggest that RhoB belongs to an emerging class of nononcogene addiction" factors that are essential for maintenance of malignant phenotypes in human cancers."
Wed Apr 01 00:00:00 UTC 2015
Ponatinib overcomes FGF2-mediated resistance in CML patients without kinase domain mutations.
Blood
Traer E,Javidi-Sharifi N,Agarwal A,Dunlap J,English I,Martinez J,Tyner JW,Wong M,Druker BJ
Thu Mar 06 00:00:00 UTC 2014
Derivation of novel human ground state naive pluripotent stem cells.
Nature
Gafni O,Weinberger L,Mansour AA,Manor YS,Chomsky E,Ben-Yosef D,Kalma Y,Viukov S,Maza I,Zviran A,Rais Y,Shipony Z,Mukamel Z,Krupalnik V,Zerbib M,Geula S,Caspi I,Schneir D,Shwartz T,Gilad S,Amann-Zalcenstein D,Benjamin S,Amit I,Tanay A,Massarwa R,Novershtern N,Hanna JH
Thu Dec 12 00:00:00 UTC 2013
Derivation of novel human ground state naive pluripotent stem cells.
Nature
Gafni O,Weinberger L,Mansour AA,Manor YS,Chomsky E,Ben-Yosef D,Kalma Y,Viukov S,Maza I,Zviran A,Rais Y,Shipony Z,Mukamel Z,Krupalnik V,Zerbib M,Geula S,Caspi I,Schneir D,Shwartz T,Gilad S,Amann-Zalcenstein D,Benjamin S,Amit I,Tanay A,Massarwa R,Novershtern N,Hanna JH
Thu Dec 12 00:00:00 UTC 2013
Deterministic direct reprogramming of somatic cells to pluripotency.
Nature
Rais Y,Zviran A,Geula S,Gafni O,Chomsky E,Viukov S,Mansour AA,Caspi I,Krupalnik V,Zerbib M,Maza I,Mor N,Baran D,Weinberger L,Jaitin DA,Lara-Astiaso D,Blecher-Gonen R,Shipony Z,Mukamel Z,Hagai T,Gilad S,Amann-Zalcenstein D,Tanay A,Amit I,Novershtern N,Hanna JH
Thu Oct 03 00:00:00 UTC 2013
Genomic instability may originate from imatinib-refractory chronic myeloid leukemia stem cells.
Blood
Bolton-Gillespie E,Schemionek M,Klein HU,Flis S,Hoser G,Lange T,Nieborowska-Skorska M,Maier J,Kerstiens L,Koptyra M,Müller MC,Modi H,Stoklosa T,Seferynska I,Bhatia R,Holyoake TL,Koschmieder S,Skorski T
Thu May 16 00:00:00 UTC 2013
