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Invitrogen
Human LIPA (aa 198-233) Control Fragment Recombinant Protein
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Product Details
RP-103288
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
FALGPVASVAFCTSPMAKLGRLPDHLIKDLFGDKEF
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
1M urea/PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (56%), Rat (56%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-84326. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
This gene encodes lipase A, the lysosomal acid lipase (also known as cholesterol ester hydrolase). This enzyme functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides. Mutations in this gene can result in Wolman disease and cholesteryl ester storage disease. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Acid cholesteryl ester hydrolase; cholesterol ester hydrolase; Cholesteryl esterase; Diacylglycerol lipase; Lipase A; lipase A, lysosomal acid, cholesterol esterase; lysosomal acid lipase; Lysosomal acid lipase/cholesteryl ester hydrolase; RP11-341B24.1; Sterol esterase; Triacylglycerol ester hydrolase; Triacylglycerol lipase
Gene Aliases: CESD; LAL; LIPA
UniProt ID: (Human) P38571
Entrez Gene ID: (Human) 3988
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