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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (84%), Rat (84%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-53064. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene encodes a protein that has a fibronectin type III domain and a C-terminal transmembrane domain, as well as a leucine-rich repeat domain and immunoglobulin-like domain near the N-terminus. The encoded protein may regulate fibroblast growth factor receptors and affect the modification of these receptors, which are glycosylated differently in the Golgi and endoplasmic reticulum. Mutations in this gene are associated with congenital stationary night blindness, type 1F.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: fibronectin type III, immunoglobulin and leucine rich repeat domains 4; leucine-rich repeat, Ig-like and transmembrane domains 3; leucine-rich repeat, immunoglobulin-like and transmembrane domains 3; Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3
Gene Aliases: CSNB1F; FIGLER4; LRIT3
UniProt ID: (Human) Q3SXY7
Entrez Gene ID: (Human) 345193
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