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Highest antigen sequence indentity to the following orthologs: Mouse (48%), Rat (48%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-52225. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Tissues with few or no mitochondria, such as erythrocytes and tumor cells, depend largely on glycolysis to generate ATP. The major end products of glycolysis, pyruvate and lactate, must be eliminated from these cells to enable continued glycolytic flux and prevent toxic effects. H+/monocarboxylate transporters mediate the transport of lactate and pyruvate. Human MCT2 has a high affinity for the transport of pyruvate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MCT 2; monocarboxylate transporter; Monocarboxylate transporter 2; solute carrier family 16 (monocarboxylate transporter), member 7; Solute carrier family 16 member 7; solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
Gene Aliases: MCT2; SLC16A7
UniProt ID: (Human) O60669
Entrez Gene ID: (Human) 9194
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