Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (87%), Rat (87%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-58408. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
ME3 proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis, metastasis, and atherosclerosis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: HME; Macrophage elastase; malate dehydrogenase; malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); Malic enzyme 3; malic enzyme 3, NADP(+)-dependent, mitochondrial; malic enzyme, NADP+-dependent, mitochondrial; ME; mitochondrial NADP(+)-dependent malic enzyme 3; MME; MMP3; NADP-dependent malic enzyme, mitochondrial; NADP-ME; pyruvic-malic carboxylase
Gene Aliases: ME3; NADP-ME
UniProt ID: (Human) Q16798
Entrez Gene ID: (Human) 10873
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