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Search Thermo Fisher Scientific
Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-64391. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
MED6 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. And mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Activator-recruited cofactor 33 kDa component; ARC33; CTD-2540L5.5; hMed6; Mediator complex subunit 6; Mediator of RNA polymerase II transcription subunit 6; Renal carcinoma antigen NY-REN-28
Gene Aliases: ARC33; MED6; NY-REN-28
UniProt ID: (Human) O75586
Entrez Gene ID: (Human) 10001
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