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Invitrogen
Human MIS18BP1 (aa 996-1119) Control Fragment Recombinant Protein
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Product Details
RP-88866
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
QHQRILLPSFQDSEDDDDILPNMDKNPTTPSSVIFPLVKTPQCQHVSPGMLGSINRNDCDKYVFRMQKYHKSNGGIVWGNIKKKLVETDFSTPTPRRKTPFNTDLGENSGIGKLFTNAVESLDE
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
1M urea/PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (57%), Rat (57%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-52306. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
MIS18BP1 is required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HsKNL-2; kinetochore null 2 homolog; Kinetochore-associated protein KNL-2 homolog; Mis18-binding protein 1; P243; putative protein p243 which interacts with transcription factor Sp1
Gene Aliases: C14orf106; HSA242977; KIAA1903; KNL2; M18BP1; MIS18BP1
UniProt ID: (Human) Q6P0N0
Entrez Gene ID: (Human) 55320
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