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Highest antigen sequence indentity to the following orthologs: Mouse (93%), Rat (93%).
This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
MSX1 is a member of the muscle segment homeobox gene family. It functions as a transcriptional repressor during embryogenesis through interactions with components of the core transcription complex and other homeoproteins. MSX1 may also have roles in limb-pattern formation, craniofacial development, particularly odontogenesis, and tumor growth inhibition. Mutations in the gene, which was once known as homeobox 7, have been associated with nonsyndromic cleft lip with or without cleft palate 5, Witkop syndrome, Wolf-Hirschom syndrome, and autosomoal dominant hypodontia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: homeobox 7; Homeobox protein Hox-7; Homeobox protein MSX-1; msh homeo box 1; Msh homeobox 1-like protein; msh homeobox homolog 1
Gene Aliases: ECTD3; HOX7; HYD1; MSX1; STHAG1
UniProt ID: (Human) P28360
Entrez Gene ID: (Human) 4487
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