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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (82%), Rat (82%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-66843. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Involved in plasma membrane dynamics. Potentiated PDGF-mediated formation of membrane ruffles and lamellipodia in fibroblasts, acting via RAC1 activation (PubMed:14752106). May function in actin bundling (PubMed:14752106). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ABBA-1; actin-bundling protein with BAIAP2 homology; Actin-bundling with BAIAP2 homology protein 1; LOC92154; metastasis suppressor 1-like; MTSS1-like protein; Protein MTSS 2
Gene Aliases: ABBA-1; ABBA1; MTSS1L; MTSS2
UniProt ID: (Human) Q765P7
Entrez Gene ID: (Human) 92154
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