Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (47%), Rat (47%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-51360. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The MUM1L1 (Melanoma Associated Antigen (Mutated) 1-Like 1) gene encodes a protein that is a member of the PWWP domain-containing family and is thought to be involved in chromatin organization and gene expression regulation. Located on chromosome Xq22.3, MUM1L1 shares homology with the oncogene MUM1, known for its roles in cancer biology, particularly in multiple myeloma and lymphomas. The PWWP domain of MUM1L1 is implicated in binding histone methylation marks, thereby influencing transcriptional activity. Although the precise biological function of MUM1L1 remains to be fully elucidated, its expression patterns suggest a role in cell proliferation and differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: melanoma associated antigen (mutated) 1-like 1; MUM1-like protein 1; Mutated melanoma-associated antigen 1-like protein 1; PWWP domain-containing DNA repair factor 3B; PWWP domain-containing protein MUM1L1; PWWP3B
Gene Aliases: MUM1L1; PWWP3B
UniProt ID: (Human) Q5H9M0
Entrez Gene ID: (Human) 139221
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