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Invitrogen
Human MYO3B (aa 269-373) Control Fragment Recombinant Protein
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Product Details
RP-102978
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
FISQCLIKDFERRPSVTHLLDHPFIKGVHGKVLFLQKQLAKVLQDQKHQNPVAKTRHERMHTRRPYHVEDAEKYCLEDDLVNLEVLDEDTIIHQLQKRYADLLIY
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
1M urea/PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (88%), Rat (88%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-61016. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
MYO3B (MYO3 beta) is a member of the Class III myosins that are actin-dependent motor proteins containing an amino-terminal kinase domain. MYO3B contains a N-terminal kinase domain, followed by motor, neck, and tail domains. The MYO3B gene generates a variety of splice variants that contain 1 or 2 calmodulin-binding (IQ) motifs in the neck domain and 1 of 3 domains in the tail domain. Northern blot analysis shows expression of a 7-kb MYO3B transcript in the human retina but not in a RPE cell line. The MYO3B gene transcript is also detected in the kidney, intestine and testis. The MYO3B gene maps to chromosome 2q31.1-q31.2 by genomic sequence alignment.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Myosin-IIIb
Gene Aliases: MYO3B
UniProt ID: (Human) Q8WXR4
Entrez Gene ID: (Human) 140469
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