Product References
Precise modulation of transcription factor levels identifies features underlying dosage sensitivity.
Nature genetics
Naqvi S,Kim S,Hoskens H,Matthews HS,Spritz RA,Klein OD,Hallgrímsson B,Swigut T,Claes P,Pritchard JK,Wysocka J
120-02 was used in In vitro experiments to propose that such REs and genes underlie the sensitivity of specific phenotypes to TF dosage, while buffering of other genes leads to robust, nonlinear dosage-to-phenotype relationships.
Mon May 01 00:00:00 UTC 2023
Effects of BAMBI on luteinized follicular granulosa cell proliferation and steroid hormone production in sheep.
Molecular reproduction and development
Zhang Y,Guo Z,Du Z,Yao Z,Guo T,Cheng Y,Wang K,Ma X,Chen C,Kebreab E,Wang D,Lyu L
120-02 was used in Cell Culture to provide a basis for further research on the physiological role of BAMBI.
Wed Mar 01 00:00:00 UTC 2023
Structural elements promote architectural stripe formation and facilitate ultra-long-range gene regulation at a human disease locus.
Molecular cell
Chen LF,Long HK,Park M,Swigut T,Boettiger AN,Wysocka J
120-02 was used in In vitro experiments to provide mechanistic insights into architectural stripe formation and gene regulation over ultra-long genomic ranges.
Thu May 04 00:00:00 UTC 2023
Dynamic expression of IGFBP3 modulate dual actions of mineralization micro-environment during tooth development via Wnt/beta-catenin signaling pathway.
Biology direct
Zhang M,Zheng J,Wu S,Chen H,Xiang L
120-02 was used in Cell Culture to demonstrate that the IGFBP3 expression is regulated in accordance with the needs of the mineralization microenvironment during tooth development, and IGFBP3 exerts its modulating action on osteogenic/odontogenic differentiation of hDPSCs by DKK1-Wnt/ beta-catenin axis.
Mon Jun 26 00:00:00 UTC 2023
Single-cell RNA sequencing reveals PDGFRα+ stromal cell subpopulations that promote proacinar cell differentiation in embryonic salivary gland organoids.
Development (Cambridge, England)
Moskwa N,Mahmood A,Nelson DA,Altrieth AL,Forni PE,Larsen M
120-02 was used in Tissue/organ culture to performe single-cell RNA-sequencing and identified multiple stromal cell subsets, including Pdgfra+ stromal subsets expressing both Fgf2 and Fgf10.
Tue Mar 15 00:00:00 UTC 2022
Culture substrate-associated YAP inactivation underlies chondrogenic differentiation of human induced pluripotent stem cells.
Stem cells translational medicine
Yamashita A,Yoshitomi H,Kihara S,Toguchida J,Tsumaki N
Fri Jan 01 00:00:00 UTC 2021
Smoc1 and Smoc2 regulate bone formation as downstream molecules of Runx2.
Communications biology
Takahata Y,Hagino H,Kimura A,Urushizaki M,Kobayashi S,Wakamori K,Fujiwara C,Nakamura E,Yu K,Kiyonari H,Bando K,Murakami T,Komori T,Hata K,Nishimura R
Tue Oct 19 00:00:00 UTC 2021
A Biomimetic Macroporous Hybrid Scaffold with Sustained Drug Delivery for Enhanced Bone Regeneration.
Biomacromolecules
Lee SS,Santschi M,Ferguson SJ
120-02 was used in In vitro experiments to evaluate drug release kinetics of CEGH and confirmed the sustained release of BMP-2.
Mon Jun 14 00:00:00 UTC 2021
Engineering large, anatomically shaped osteochondral constructs with robust interfacial shear properties.
NPJ Regenerative medicine
Brown WE,Huang BJ,Hu JC,Athanasiou KA
Fri Aug 06 00:00:00 UTC 2021
BMP-2 and VEGF-A modRNAs in collagen scaffold synergistically drive bone repair through osteogenic and angiogenic pathways.
Communications biology
Geng Y,Duan H,Xu L,Witman N,Yan B,Yu Z,Wang H,Tan Y,Lin L,Li D,Bai S,Fritsche-Danielson R,Yuan J,Chien K,Wei M,Fu W
Tue Jan 19 00:00:00 UTC 2021
Sequential dual-drug delivery of BMP-2 and alendronate from hydroxyapatite-collagen scaffolds for enhanced bone regeneration.
Scientific reports
Lee D,Wufuer M,Kim I,Choi TH,Kim BJ,Jung HG,Jeon B,Lee G,Jeon OH,Chang H,Yoon DS
Tue Jan 12 00:00:00 UTC 2021
BMSC-derived extracellular vesicles intervened the pathogenic changes of scleroderma in mice through miRNAs.
Stem cell research & therapy
Jin J,Ou Q,Wang Z,Tian H,Xu JY,Gao F,Hu S,Chen J,Wang J,Zhang J,Lu L,Jin C,Xu GT,Zhao J
120-02 was used in Cell Culture to investigate development of skin cells and bone-marrow mesenchymal stem cells in systemic sclerosis.
Sat Jun 05 00:00:00 UTC 2021
Thyroid Hormone Effect on the Differentiation of Human Induced Pluripotent Stem Cells into Hepatocyte-Like Cells.
Pharmaceuticals (Basel, Switzerland)
Bogacheva MS,Bystriakova MA,Lou YR
120-02 was used in Sample Preparation (Western Blotting) to investigate hepatocyte-like cell culture from induced pluripotent stem cells for future therapeutic treatment.
Mon Jun 07 00:00:00 UTC 2021
Thyroid Hormone Effect on the Differentiation of Human Induced Pluripotent Stem Cells into Hepatocyte-Like Cells.
Pharmaceuticals (Basel, Switzerland)
Bogacheva MS,Bystriakova MA,Lou YR
120-02 was used in Sample Preparation (Western Blotting) to investigate hepatocyte-like cell culture from induced pluripotent stem cells for future therapeutic treatment.
Mon Jun 07 00:00:00 UTC 2021
CDC5L promotes early chondrocyte differentiation and proliferation by modulating pre-mRNA splicing of SOX9, COL2A1, and WEE1.
The Journal of biological chemistry
Jokoji G,Maeda S,Oishi K,Ijuin T,Nakajima M,Tawaratsumida H,Kawamura I,Tominaga H,Taketomi E,Ikegawa S,Taniguchi N
Sun Aug 01 00:00:00 UTC 2021
Personalized medicine for reconstruction of critical-size bone defects - a translational approach with customizable vascularized bone tissue.
NPJ Regenerative medicine
Kengelbach-Weigand A,Thielen C,Bäuerle T,Götzl R,Gerber T,Körner C,Beier JP,Horch RE,Boos AM
Thu Aug 19 00:00:00 UTC 2021
Cohesin-protein Shugoshin-1 controls cardiac automaticity via HCN4 pacemaker channel.
Nature communications
Liu D,Song AT,Qi X,van Vliet PP,Xiao J,Xiong F,Andelfinger G,Nattel S
Wed May 05 00:00:00 UTC 2021
Osteogenic differentiation of human mesenchymal stromal cells and fibroblasts differs depending on tissue origin and replicative senescence.
Scientific reports
Grotheer V,Skrynecki N,Oezel L,Windolf J,Grassmann J
Mon Jun 07 00:00:00 UTC 2021
SARS-CoV-2 productively infects human gut enterocytes.
Science (New York, N.Y.)
Lamers MM,Beumer J,van der Vaart J,Knoops K,Puschhof J,Breugem TI,Ravelli RBG,Paul van Schayck J,Mykytyn AZ,Duimel HQ,van Donselaar E,Riesebosch S,Kuijpers HJH,Schipper D,van de Wetering WJ,de Graaf M,Koopmans M,Cuppen E,Peters PJ,Haagmans BL,Clevers H
Fri Jul 03 00:00:00 UTC 2020
BMP-induced Atoh8 attenuates osteoclastogenesis by suppressing Runx2 transcriptional activity and reducing the Rankl/Opg expression ratio in osteoblasts.
Bone research
Yahiro Y,Maeda S,Morikawa M,Koinuma D,Jokoji G,Ijuin T,Komiya S,Kageyama R,Miyazono K,Taniguchi N
Mon May 01 00:00:00 UTC 2023
Bmp2 regulates Serpinb6b expression via cAMP/PKA/Wnt4 pathway during uterine decidualization.
Journal of cellular and molecular medicine
Yu HF,Zheng LW,Yang ZQ,Wang YS,Huang JC,Liu S,Yue ZP,Guo B
Mon Jun 01 00:00:00 UTC 2020
Deficiency of Macf1 in osterix expressing cells decreases bone formation by Bmp2/Smad/Runx2 pathway.
Journal of cellular and molecular medicine
Qiu WX,Ma XL,Lin X,Zhao F,Li DJ,Chen ZH,Zhang KW,Zhang R,Wang P,Xiao YY,Miao ZP,Dang K,Wu XY,Qian AR
Wed Jan 01 00:00:00 UTC 2020
Generation of an induced pluripotent stem cell line (DANi-011A) from a Parkinson's disease patient with a LRRK2 p.G2019S mutation.
Stem cell research
Chen M,Maimaitili M,Buchholdt SH,Jensen UB,Febbraro F,Denham M
120-02 was used in Cell Culture to show that the expression of pluripotent markers in the iPSC line was confirmed by immunofluorescent staining, and we confirmed its ability to differentiate into the three germ layers.
Fri May 01 00:00:00 UTC 2020
Quality assessment tests for tumorigenicity of human iPS cell-derived cartilage.
Scientific reports
Takei Y,Morioka M,Yamashita A,Kobayashi T,Shima N,Tsumaki N
Thu Jul 30 00:00:00 UTC 2020
TGF-β regulates Sca-1 expression and plasticity of pre-neoplastic mammary epithelial stem cells.
Scientific reports
Remšík J,Pícková M,Vacek O,Fedr R,Binó L,Hampl A,Souček K
Thu Jul 09 00:00:00 UTC 2020
Single Amino Acid Change Underlies Distinct Roles of H2A.Z Subtypes in Human Syndrome.
Cell
Greenberg RS,Long HK,Swigut T,Wysocka J
Thu Sep 05 00:00:00 UTC 2019
PTEN-induced partial epithelial-mesenchymal transition drives diabetic kidney disease.
The Journal of clinical investigation
Li Y,Hu Q,Li C,Liang K,Xiang Y,Hsiao H,Nguyen TK,Park PK,Egranov SD,Ambati CR,Putluri N,Hawke DH,Han L,Hung MC,Danesh FR,Yang L,Lin C
Fri Mar 01 00:00:00 UTC 2019
Herbacetin treatment remitted LPS induced inhibition of osteoblast differentiation through blocking AKT/NF-κB signaling pathway.
American journal of translational research
Cai P,Cai T,Li X,Fan L,Chen G,Yu B,Liu T
120-02 was used in Cell Culture to study the role and molecular mechanism of Herbacetin in the process of osteoblast differentiation under LPS-mediated inflammatory environment to suggest that Herbacetin might play a protective role in osteoblast differentiation in MC3T3-E1/C2C12/PMCO cells under LPS stimulation.
Thu Oct 01 00:00:00 UTC 2020
Excessive mechanical loading promotes osteoarthritis through the gremlin-1-NF-κB pathway.
Nature communications
Chang SH,Mori D,Kobayashi H,Mori Y,Nakamoto H,Okada K,Taniguchi Y,Sugita S,Yano F,Chung UI,Kim-Kaneyama JR,Yanagita M,Economides A,Canalis E,Chen D,Tanaka S,Saito T
Fri Mar 29 00:00:00 UTC 2019
Excessive mechanical loading promotes osteoarthritis through the gremlin-1-NF-κB pathway.
Nature communications
Chang SH,Mori D,Kobayashi H,Mori Y,Nakamoto H,Okada K,Taniguchi Y,Sugita S,Yano F,Chung UI,Kim-Kaneyama JR,Yanagita M,Economides A,Canalis E,Chen D,Tanaka S,Saito T
Fri Mar 29 00:00:00 UTC 2019
TGF-β2 uses the concave surface of its extended finger region to bind betaglycan's ZP domain via three residues specific to TGF-β and inhibin-α.
The Journal of biological chemistry
Henen MA,Mahlawat P,Zwieb C,Kodali RB,Hinck CS,Hanna RD,Krzysiak TC,Ilangovan U,Cano KE,Hinck G,Vonberg M,McCabe M,Hinck AP
Fri Mar 01 00:00:00 UTC 2019
PDGF Modulates BMP2-Induced Osteogenesis in Periosteal Progenitor Cells.
JBMR plus
Wang X,Matthews BG,Yu J,Novak S,Grcevic D,Sanjay A,Kalajzic I
Wed May 01 00:00:00 UTC 2019
The Spatiotemporal Pattern and Intensity of p53 Activation Dictates Phenotypic Diversity in p53-Driven Developmental Syndromes.
Developmental cell
Bowen ME,McClendon J,Long HK,Sorayya A,Van Nostrand JL,Wysocka J,Attardi LD
120-02 was used in Cell Culture to study the basis of p53-driven developmental syndromes by leveraging an array of mouse strains to modulate the spatial expression pattern, temporal profile, and magnitude of p53 activation during embryogenesis.
Mon Jul 22 00:00:00 UTC 2019
A change in the zinc ion concentration reflects the maturation of insulin-producing cells generated from adipose-derived mesenchymal stem cells.
Scientific reports
Ohta S,Ikemoto T,Wada Y,Saito Y,Yamada S,Imura S,Morine Y,Shimada M
Tue Dec 10 00:00:00 UTC 2019
Cardiotrophin-like cytokine (CLCF1) modulates mesenchymal stem cell osteoblastic differentiation.
The Journal of biological chemistry
Nahlé S,Pasquin S,Laplante V,Rousseau F,Sharma M,Gauchat JF
Fri Aug 09 00:00:00 UTC 2019
Bone-conditioned medium contributes to initiation and progression of osteogenesis by exhibiting synergistic TGF-β1/BMP-2 activity.
International journal of oral science
Asparuhova MB,Caballé-Serrano J,Buser D,Chappuis V
Tue Jun 12 00:00:00 UTC 2018
Selective serotonin re-uptake inhibitor sertraline inhibits bone healing in a calvarial defect model.
International journal of oral science
Howie RN,Herberg S,Durham E,Grey Z,Bennfors G,Elsalanty M,LaRue AC,Hill WD,Cray JJ
Mon Sep 03 00:00:00 UTC 2018
Combinatorial CRISPR/Cas9 Approach to Elucidate a Far-Upstream Enhancer Complex for Tissue-Specific Sox9 Expression.
Developmental cell
Mochizuki Y,Chiba T,Kataoka K,Yamashita S,Sato T,Kato T,Takahashi K,Miyamoto T,Kitazawa M,Hatta T,Natsume T,Takai S,Asahara H
120-02 was used in Cell Culture to identify a critical far-upstream cis-element and Stat3 as a trans-acting factor, regulating cartilage-specific Sox9 expression and subsequent skeletal development.
Mon Sep 24 00:00:00 UTC 2018
BMP-2 induces human mononuclear cell chemotaxis and adhesion and modulates monocyte-to-macrophage differentiation.
Journal of cellular and molecular medicine
Pardali E,Makowski LM,Leffers M,Borgscheiper A,Waltenberger J
Thu Nov 01 00:00:00 UTC 2018
BMP and WNT signalling cooperate through LEF1 in the neuronal specification of adult hippocampal neural stem and progenitor cells.
Scientific reports
Armenteros T,Andreu Z,Hortigüela R,Lie DC,Mira H
Mon Jun 18 00:00:00 UTC 2018
Laminin heparin-binding peptides bind to several growth factors and enhance diabetic wound healing.
Nature communications
Ishihara J,Ishihara A,Fukunaga K,Sasaki K,White MJV,Briquez PS,Hubbell JA
Mon Jun 04 00:00:00 UTC 2018
Laminin heparin-binding peptides bind to several growth factors and enhance diabetic wound healing.
Nature communications
Ishihara J,Ishihara A,Fukunaga K,Sasaki K,White MJV,Briquez PS,Hubbell JA
Mon Jun 04 00:00:00 UTC 2018
Generation of Adrenal Chromaffin-like Cells from Human Pluripotent Stem Cells.
Stem cell reports
Abu-Bonsrah KD,Zhang D,Bjorksten AR,Dottori M,Newgreen DF
Tue Jan 09 00:00:00 UTC 2018
Phenotypic and Functional Characterization of Peripheral Sensory Neurons derived from Human Embryonic Stem Cells.
Scientific reports
Alshawaf AJ,Viventi S,Qiu W,D'Abaco G,Nayagam B,Erlichster M,Chana G,Everall I,Ivanusic J,Skafidas E,Dottori M
Fri Jan 12 00:00:00 UTC 2018
Generation of an osteoblast-based artificial niche that supports in vitro B lymphopoiesis.
Experimental & molecular medicine
Yu J,Choi S,Kim H,Lee N,Yun H,Kim S,Jeong ST,Rho J
Fri Nov 24 00:00:00 UTC 2017
Adult cardiac stem cells are multipotent and robustly myogenic: c-kit expression is necessary but not sufficient for their identification.
Cell death and differentiation
Vicinanza C,Aquila I,Scalise M,Cristiano F,Marino F,Cianflone E,Mancuso T,Marotta P,Sacco W,Lewis FC,Couch L,Shone V,Gritti G,Torella A,Smith AJ,Terracciano CM,Britti D,Veltri P,Indolfi C,Nadal-Ginard B,Ellison-Hughes GM,Torella D
Fri Dec 01 00:00:00 UTC 2017
Oncostatin M promotes cancer cell plasticity through cooperative STAT3-SMAD3 signaling.
Oncogene
Junk DJ,Bryson BL,Smigiel JM,Parameswaran N,Bartel CA,Jackson MW
120-02 was used in Sample Preparation to study the specific tumor microenvironment (TME) which most actively control cancer cell plasticity for metastasis.
Thu Jul 13 00:00:00 UTC 2017
Oncostatin M promotes cancer cell plasticity through cooperative STAT3-SMAD3 signaling.
Oncogene
Junk DJ,Bryson BL,Smigiel JM,Parameswaran N,Bartel CA,Jackson MW
120-02 was used in Sample Preparation to study the specific tumor microenvironment (TME) which most actively control cancer cell plasticity for metastasis.
Thu Jul 13 00:00:00 UTC 2017
Growth factors regulate phospholipid biosynthesis in human fibroblast-like synoviocytes obtained from osteoarthritic knees.
Scientific reports
Sluzalska KD,Liebisch G,Wilhelm J,Ishaque B,Hackstein H,Schmitz G,Rickert M,Steinmeyer J
Wed Oct 18 00:00:00 UTC 2017
Interleukin-1β (IL-1β) transcriptionally activates hepcidin by inducing CCAAT enhancer-binding protein δ (C/EBPδ) expression in hepatocytes.
The Journal of biological chemistry
Kanamori Y,Murakami M,Sugiyama M,Hashimoto O,Matsui T,Funaba M
Fri Jun 16 00:00:00 UTC 2017
Colloidal Gels with Extracellular Matrix Particles and Growth Factors for Bone Regeneration in Critical Size Rat Calvarial Defects.
The AAPS journal
Townsend JM,Dennis SC,Whitlow J,Feng Y,Wang J,Andrews B,Nudo RJ,Detamore MS,Berkland CJ
120-02 was used in In vitro experiments to study the development of a novel colloidal gel as a commercially available product for craniofacial reconstruction.
Mon May 01 00:00:00 UTC 2017
Restoring Ureagenesis in Hepatocytes by CRISPR/Cas9-mediated Genomic Addition to Arginase-deficient Induced Pluripotent Stem Cells.
Molecular therapy. Nucleic acids
Lee PC,Truong B,Vega-Crespo A,Gilmore WB,Hermann K,Angarita SA,Tang JK,Chang KM,Wininger AE,Lam AK,Schoenberg BE,Cederbaum SD,Pyle AD,Byrne JA,Lipshutz GS
Tue Nov 29 00:00:00 UTC 2016
Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3.
Nature communications
Yahara Y,Takemori H,Okada M,Kosai A,Yamashita A,Kobayashi T,Fujita K,Itoh Y,Nakamura M,Fuchino H,Kawahara N,Fukui N,Watanabe A,Kimura T,Tsumaki N
Thu Mar 24 00:00:00 UTC 2016
Notch signaling indirectly promotes chondrocyte hypertrophy via regulation of BMP signaling and cell cycle arrest.
Scientific reports
Shang X,Wang J,Luo Z,Wang Y,Morandi MM,Marymont JV,Hilton MJ,Dong Y
Thu May 05 00:00:00 UTC 2016
Glycomic Characterization of Induced Pluripotent Stem Cells Derived from a Patient Suffering from Phosphomannomutase 2 Congenital Disorder of Glycosylation (PMM2-CDG).
Molecular & cellular proteomics : MCP
Thiesler CT,Cajic S,Hoffmann D,Thiel C,van Diepen L,Hennig R,Sgodda M,Weiβmann R,Reichl U,Steinemann D,Diekmann U,Huber NM,Oberbeck A,Cantz T,Kuss AW,Körner C,Schambach A,Rapp E,Buettner FF
Fri Apr 01 00:00:00 UTC 2016
p38 MAPK regulates the Wnt inhibitor Dickkopf-1 in osteotropic prostate cancer cells.
Cell death & disease
Browne AJ,Göbel A,Thiele S,Hofbauer LC,Rauner M,Rachner TD
Thu Feb 25 00:00:00 UTC 2016
Intra-articular injection of synovial mesenchymal stem cells improves cartilage repair in a mouse injury model.
Scientific reports
Mak J,Jablonski CL,Leonard CA,Dunn JF,Raharjo E,Matyas JR,Biernaskie J,Krawetz RJ
Thu Mar 17 00:00:00 UTC 2016
Integrating Epigenomic Elements and GWASs Identifies BDNF Gene Affecting Bone Mineral Density and Osteoporotic Fracture Risk.
Scientific reports
Guo Y,Dong SS,Chen XF,Jing YA,Yang M,Yan H,Shen H,Chen XD,Tan LJ,Tian Q,Deng HW,Yang TL
Thu Jul 28 00:00:00 UTC 2016
Generating trunk neural crest from human pluripotent stem cells.
Scientific reports
Huang M,Miller ML,McHenry LK,Zheng T,Zhen Q,Ilkhanizadeh S,Conklin BR,Bronner ME,Weiss WA
Wed Jan 27 00:00:00 UTC 2016
Multipotent caudal neural progenitors derived from human pluripotent stem cells that give rise to lineages of the central and peripheral nervous system.
Stem cells (Dayton, Ohio)
Denham M,Hasegawa K,Menheniott T,Rollo B,Zhang D,Hough S,Alshawaf A,Febbraro F,Ighaniyan S,Leung J,Elliott DA,Newgreen DF,Pera MF,Dottori M
Mon Jun 01 00:00:00 UTC 2015
TGF-β1, but not bone morphogenetic proteins, activates Smad1/5 pathway in primary human macrophages and induces expression of proatherogenic genes.
Journal of immunology (Baltimore, Md. : 1950)
Nurgazieva D,Mickley A,Moganti K,Ming W,Ovsyi I,Popova A,Awad K,Wang N,Bieback K,Goerdt S,Kzhyshkowska J,Gratchev A
Thu Jan 15 00:00:00 UTC 2015
PI3K/mTORC2 regulates TGF-β/Activin signalling by modulating Smad2/3 activity via linker phosphorylation.
Nature communications
Yu JS,Ramasamy TS,Murphy N,Holt MK,Czapiewski R,Wei SK,Cui W
Fri May 22 00:00:00 UTC 2015
ELL Protein-associated Factor 2 (EAF2) Inhibits Transforming Growth Factor β Signaling through a Direct Interaction with Smad3.
The Journal of biological chemistry
Liu X,Chen Z,Ouyang G,Song T,Liang H,Liu W,Xiao W
Fri Oct 23 00:00:00 UTC 2015
Cigarette smoking hinders human periodontal ligament-derived stem cell proliferation, migration and differentiation potentials.
Scientific reports
Ng TK,Huang L,Cao D,Yip YW,Tsang WM,Yam GH,Pang CP,Cheung HS
Fri Jan 16 00:00:00 UTC 2015
Statin treatment rescues FGFR3 skeletal dysplasia phenotypes.
Nature
Yamashita A,Morioka M,Kishi H,Kimura T,Yahara Y,Okada M,Fujita K,Sawai H,Ikegawa S,Tsumaki N
Thu Sep 25 00:00:00 UTC 2014
Crosstalk between muscularis macrophages and enteric neurons regulates gastrointestinal motility.
Cell
Muller PA,Koscsó B,Rajani GM,Stevanovic K,Berres ML,Hashimoto D,Mortha A,Leboeuf M,Li XM,Mucida D,Stanley ER,Dahan S,Margolis KG,Gershon MD,Merad M,Bogunovic M
Thu Jul 17 00:00:00 UTC 2014
Opposing TNF-α/IL-1β- and BMP-2-activated MAPK signaling pathways converge on Runx2 to regulate BMP-2-induced osteoblastic differentiation.
Cell death & disease
Huang RL,Yuan Y,Tu J,Zou GM,Li Q
Thu Apr 17 00:00:00 UTC 2014
Bone morphogenic protein (BMP) signaling up-regulates neutral sphingomyelinase 2 to suppress chondrocyte maturation via the Akt protein signaling pathway as a negative feedback mechanism.
The Journal of biological chemistry
Kakoi H,Maeda S,Shinohara N,Matsuyama K,Imamura K,Kawamura I,Nagano S,Setoguchi T,Yokouchi M,Ishidou Y,Komiya S
Fri Mar 21 00:00:00 UTC 2014
Human immunodeficiency virus type 1 enhancer-binding protein 3 is essential for the expression of asparagine-linked glycosylation 2 in the regulation of osteoblast and chondrocyte differentiation.
The Journal of biological chemistry
Imamura K,Maeda S,Kawamura I,Matsuyama K,Shinohara N,Yahiro Y,Nagano S,Setoguchi T,Yokouchi M,Ishidou Y,Komiya S
Fri Apr 04 00:00:00 UTC 2014
Differentiation of human skeletal muscle stem cells into odontoblasts is dependent on induction of α1 integrin expression.
The Journal of biological chemistry
Ozeki N,Mogi M,Yamaguchi H,Hiyama T,Kawai R,Hase N,Nakata K,Nakamura H,Kramer RH
Fri May 16 00:00:00 UTC 2014
Heparin-binding domain of fibrin(ogen) binds growth factors and promotes tissue repair when incorporated within a synthetic matrix.
Proceedings of the National Academy of Sciences of the United States of America
Martino MM,Briquez PS,Ranga A,Lutolf MP,Hubbell JA
Tue Mar 19 00:00:00 UTC 2013
The transcription factors Tbx18 and Wt1 control the epicardial epithelial-mesenchymal transition through bi-directional regulation of Slug in murine primary epicardial cells.
PloS one
Takeichi M,Nimura K,Mori M,Nakagami H,Kaneda Y
Thu Aug 29 00:00:00 UTC 2013
EB1 levels are elevated in ascorbic Acid (AA)-stimulated osteoblasts and mediate cell-cell adhesion-induced osteoblast differentiation.
The Journal of biological chemistry
Pustylnik S,Fiorino C,Nabavi N,Zappitelli T,da Silva R,Aubin JE,Harrison RE
Fri Jul 26 00:00:00 UTC 2013
Guiding the osteogenic fate of mouse and human mesenchymal stem cells through feedback system control.
Scientific reports
Honda Y,Ding X,Mussano F,Wiberg A,Ho CM,Nishimura I
Thu Dec 05 00:00:00 UTC 2013
Guiding the osteogenic fate of mouse and human mesenchymal stem cells through feedback system control.
Scientific reports
Honda Y,Ding X,Mussano F,Wiberg A,Ho CM,Nishimura I
Thu Dec 05 00:00:00 UTC 2013
Derivation of iPSCs in stirred suspension bioreactors.
Nature methods
Shafa M,Day B,Yamashita A,Meng G,Liu S,Krawetz R,Rancourt DE
Sun Apr 08 00:00:00 UTC 2012
Signaling crosstalk between TGFβ and Dishevelled/Par1b.
Cell death and differentiation
Mamidi A,Inui M,Manfrin A,Soligo S,Enzo E,Aragona M,Cordenonsi M,Wessely O,Dupont S,Piccolo S
Mon Oct 01 00:00:00 UTC 2012
The crosstalk between transforming growth factor-β1 and delta like-1 mediates early chondrogenesis during embryonic endochondral ossification.
Stem cells (Dayton, Ohio)
Taipaleenmäki H,Harkness L,Chen L,Larsen KH,Säämänen AM,Kassem M,Abdallah BM
Wed Feb 01 00:00:00 UTC 2012
Noggin recruits mesoderm progenitors from the dorsal aorta to a skeletal myogenic fate.
Developmental biology
Ugarte G,Cappellari O,Perani L,Pistocchi A,Cossu G
Tue May 01 00:00:00 UTC 2012
SnoN suppresses maturation of chondrocytes by mediating signal cross-talk between transforming growth factor-β and bone morphogenetic protein pathways.
The Journal of biological chemistry
Kawamura I,Maeda S,Imamura K,Setoguchi T,Yokouchi M,Ishidou Y,Komiya S
Fri Aug 17 00:00:00 UTC 2012
Transforming growth factor β1 inhibits bone morphogenic protein (BMP)-2 and BMP-7 signaling via upregulation of Ski-related novel protein N (SnoN): possible mechanism for the failure of BMP therapy?
BMC medicine
Ehnert S,Zhao J,Pscherer S,Freude T,Dooley S,Kolk A,Stöckle U,Nussler AK,Hube R
Fri Sep 07 00:00:00 UTC 2012
Synovial fluid progenitors expressing CD90+ from normal but not osteoarthritic joints undergo chondrogenic differentiation without micro-mass culture.
PloS one
Krawetz RJ,Wu YE,Martin L,Rattner JB,Matyas JR,Hart DA
Tue Feb 19 00:00:00 UTC 2013
Involvement of twisted gastrulation in T cell-independent plasma cell production.
Journal of immunology (Baltimore, Md. : 1950)
Tsalavos S,Segklia K,Passa O,Petryk A,O'Connor MB,Graf D
Wed Jun 15 00:00:00 UTC 2011
Involvement of twisted gastrulation in T cell-independent plasma cell production.
Journal of immunology (Baltimore, Md. : 1950)
Tsalavos S,Segklia K,Passa O,Petryk A,O'Connor MB,Graf D
Wed Jun 15 00:00:00 UTC 2011
Pivotal role of the C2 domain of the Smurf1 ubiquitin ligase in substrate selection.
The Journal of biological chemistry
Lu K,Li P,Zhang M,Xing G,Li X,Zhou W,Bartlam M,Zhang L,Rao Z,He F
Fri May 13 00:00:00 UTC 2011
A Runx2/miR-3960/miR-2861 regulatory feedback loop during mouse osteoblast differentiation.
The Journal of biological chemistry
Hu R,Liu W,Li H,Yang L,Chen C,Xia ZY,Guo LJ,Xie H,Zhou HD,Wu XP,Luo XH
Fri Apr 08 00:00:00 UTC 2011
Differential growth factor adsorption to calvarial osteoblast-secreted extracellular matrices instructs osteoblastic behavior.
PloS one
Bhat A,Boyadjiev SA,Senders CW,Leach JK
Mon Feb 13 00:00:00 UTC 2012
Isolation of mouse mesenchymal stem cells with normal ploidy from bone marrows by reducing oxidative stress in combination with extracellular matrix.
BMC cell biology
Fan G,Wen L,Li M,Li C,Luo B,Wang F,Zhou L,Liu L
Wed Jul 06 00:00:00 UTC 2011
In vitro model of vascularized bone: synergizing vascular development and osteogenesis.
PloS one
Correia C,Grayson WL,Park M,Hutton D,Zhou B,Guo XE,Niklason L,Sousa RA,Reis RL,Vunjak-Novakovic G
Fri Jul 20 00:00:00 UTC 2012
A secreted BMP antagonist, Cer1, fine tunes the spatial organization of the ureteric bud tree during mouse kidney development.
PloS one
Chi L,Saarela U,Railo A,Prunskaite-Hyyryläinen R,Skovorodkin I,Anthony S,Katsu K,Liu Y,Shan J,Salgueiro AM,Belo JA,Davies J,Yokouchi Y,Vainio SJ
Thu May 03 00:00:00 UTC 2012
Formation of stable homomeric and transient heteromeric bone morphogenetic protein (BMP) receptor complexes regulates Smad protein signaling.
The Journal of biological chemistry
Marom B,Heining E,Knaus P,Henis YI
Fri Jun 03 00:00:00 UTC 2011
Transcriptional control of preadipocyte determination by Zfp423.
Nature
Gupta RK,Arany Z,Seale P,Mepani RJ,Ye L,Conroe HM,Roby YA,Kulaga H,Reed RR,Spiegelman BM
Thu Mar 25 00:00:00 UTC 2010
Human multipotent mesenchymal stromal cells use galectin-1 to inhibit immune effector cells.
Blood
Gieseke F,Böhringer J,Bussolari R,Dominici M,Handgretinger R,Müller I
Thu Nov 11 00:00:00 UTC 2010
The LARGE principle of cellular reprogramming: lost, acquired and retained gene expression in foreskin and amniotic fluid-derived human iPS cells.
PloS one
Wolfrum K,Wang Y,Prigione A,Sperling K,Lehrach H,Adjaye J
Fri Oct 29 00:00:00 UTC 2010
Partial dysferlin reconstitution by adult murine mesoangioblasts is sufficient for full functional recovery in a murine model of dysferlinopathy.
Cell death & disease
Díaz-Manera J,Touvier T,Dellavalle A,Tonlorenzi R,Tedesco FS,Messina G,Meregalli M,Navarro C,Perani L,Bonfanti C,Illa I,Torrente Y,Cossu G
Thu Aug 05 00:00:00 UTC 2010
Identification of five developmental processes during chondrogenic differentiation of embryonic stem cells.
PloS one
Yamashita A,Nishikawa S,Rancourt DE
Mon Jun 07 00:00:00 UTC 2010
Mechanical stress activates Smad pathway through PKCδ to enhance interleukin-11 gene transcription in osteoblasts.
PloS one
Kido S,Kuriwaka-Kido R,Umino-Miyatani Y,Endo I,Inoue D,Taniguchi H,Inoue Y,Imamura T,Matsumoto T
Wed Sep 29 00:00:00 UTC 2010
FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination.
Cell
Dupont S,Mamidi A,Cordenonsi M,Montagner M,Zacchigna L,Adorno M,Martello G,Stinchfield MJ,Soligo S,Morsut L,Inui M,Moro S,Modena N,Argenton F,Newfeld SJ,Piccolo S
Fri Jan 09 00:00:00 UTC 2009
Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells.
Cell research
Song Z,Cai J,Liu Y,Zhao D,Yong J,Duo S,Song X,Guo Y,Zhao Y,Qin H,Yin X,Wu C,Che J,Lu S,Ding M,Deng H
Sun Nov 01 00:00:00 UTC 2009
Loss of discordant cells during micro-mass differentiation of embryonic stem cells into the chondrocyte lineage.
Cell death and differentiation
Yamashita A,Krawetz R,Rancourt DE
Sun Feb 01 00:00:00 UTC 2009
Chemokine-mediated migration of skin-derived stem cells: predominant role for CCL5/RANTES.
The Journal of investigative dermatology
Kroeze KL,Jurgens WJ,Doulabi BZ,van Milligen FJ,Scheper RJ,Gibbs S
Mon Jun 01 00:00:00 UTC 2009
Functional neurons and melanocytes induced from immortal lines of postnatal neural crest-like stem cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Sviderskaya EV,Easty DJ,Lawrence MA,Sánchez DP,Negulyaev YA,Patel RH,Anand P,Korchev YE,Bennett DC
Tue Sep 01 00:00:00 UTC 2009
Dose effect of dual delivery of vascular endothelial growth factor and bone morphogenetic protein-2 on bone regeneration in a rat critical-size defect model.
Tissue engineering. Part A
Young S,Patel ZS,Kretlow JD,Murphy MB,Mountziaris PM,Baggett LS,Ueda H,Tabata Y,Jansen JA,Wong M,Mikos AG
Tue Sep 01 00:00:00 UTC 2009
Differential effects of bone morphogenetic protein-2 and transforming growth factor-beta1 on gene expression of collagen-modifying enzymes in human adipose tissue-derived mesenchymal stem cells.
Tissue engineering. Part A
Knippenberg M,Helder MN,Doulabi BZ,Bank RA,Wuisman PI,Klein-Nulend J
Sat Aug 01 00:00:00 UTC 2009
Negative feedback Inhibition of NFATc1 by DYRK1A regulates bone homeostasis.
The Journal of biological chemistry
Lee Y,Ha J,Kim HJ,Kim YS,Chang EJ,Song WJ,Kim HH
Fri Nov 27 00:00:00 UTC 2009
Diverse bone morphogenetic protein expression profiles and smad pathway activation in different phenotypes of experimental canine mammary tumors.
PloS one
Wensman H,Heldin NE,Pejler G,Hellmén E
Tue Sep 22 00:00:00 UTC 2009
Bone morphogenetic protein-2: a potential regulator in scleral remodeling.
Molecular vision
Hu J,Cui D,Yang X,Wang S,Hu S,Li C,Zeng J
Mon Mar 23 00:00:00 UTC 2009
Enhanced bone regeneration with BMP-2 loaded functional nanoparticle-hydrogel complex.
Journal of controlled release : official journal of the Controlled Release Society
Chung YI,Ahn KM,Jeon SH,Lee SY,Lee JH,Tae G
Thu Aug 16 00:00:00 UTC 2007
Myeloma cells block RUNX2/CBFA1 activity in human bone marrow osteoblast progenitors and inhibit osteoblast formation and differentiation.
Blood
Giuliani N,Colla S,Morandi F,Lazzaretti M,Sala R,Bonomini S,Grano M,Colucci S,Svaldi M,Rizzoli V
Sat Oct 01 00:00:00 UTC 2005
