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Invitrogen
Human NBPF15 (aa 373-397) Control Fragment Recombinant Protein
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Product Details
RP-108172
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
SGCLELTDSCQPYRSAFYVLEQQRV
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
1M urea/PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (40%), Rat (40%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-83644. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
NBPF15 (NBPF Member 15), located on 1q21.1, is a Protein Coding gene. This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family contains numerous pseudogenes. Human NBPF15 encodes a 670 AA protein consisting of six clades of Olduvai domains. The entanglements between the mosaic disorder-ordered segments in the NBPF15 N terminus have triggered the multiple types of aggregates and phase transition of NBPF15 proteins, which could be associated with Olduvai-related cognitive dysfunction diseases. Diseases associated with NBPF15 include Neuroblastoma and Hydrolethalus Syndrome 1. An important paralog of this gene is NBPF14.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AB14; NBPF; NBPF family member NBPF15; NBPF Member 15; Neuroblastoma breakpoint family member 15; Neuroblastoma breakpoint family member 16; Neuroblastoma Breakpoint Family, Member 1; neuroblastoma breakpoint family, member 15; Neuroblastoma Breakpoint Family, Member 16
Gene Aliases: AB14; AG3; NBPF15; NBPF16
UniProt ID: (Human) Q8N660
Entrez Gene ID: (Human) 284565
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