Invitrogen

Human NIPA2 Control Fragment Recombinant Protein

Product Details

RP-105532

Applications

Tested Dilution

Publications

Control (Ctrl)

Assay-dependent

Blocking Assay (BLOCK)

Assay-dependent

Product Specifications

Species

Human

Expression System

E. coli

Amino acid sequence

LESLPVSFRKDEKAMNGNLSNMYEVLNNNEES

Tag

His-ABP-tag

Class

Recombinant

Type

Protein

Purity

>80% by SDS-PAGE and Coomassie blue staining

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

≥5.0 mg/mL

Purification

purified

Storage buffer

PBS/1M urea, pH 7.4

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Product Specific Information

Highest antigen sequence indentity to the following orthologs: Mouse (88%), Rat (88%).

This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-67168. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Target Information

Nipa2 encodes a protein that acts as a selective Mg(2+) transporter. The Nipa2 gene encodes a possible magnesium transporter, and is located adjacent to the imprinted domain in the Prader-Willi syndrome deletion region of chromosome 15. Alternate splicing of the Nipa2 gene results in multiple transcript variants. Pseudogenes of the Nipa2 gene are found on chromosomes 3, 7 and 21. Diseases associated with NIPA2 include Angelman Syndrome and Prader-Willi Syndrome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Magnesium transporter NIPA2; Non-imprinted in Prader-Willi/Angelman syndrome region protein 2