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Highest antigen sequence indentity to the following orthologs: Mouse (37%), Rat (37%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-53663. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene is a receptor for opioid growth factor (OGF), also known as [Met(5)]-enkephalin. OGF is a negative regulator of cell proliferation and tissue organization in a variety of processes. The encoded unbound receptor for OGF has been localized to the outer nuclear envelope, where it binds OGF and is translocated into the nucleus. The coding sequence of this gene contains a polymorphic region of 60 nt tandem imperfect repeat units. Several transcripts containing between zero and eight repeat units have been reported. [provided by RefSeq, Jul 2008].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 7-60 protein; OGFr; Opioid growth factor receptor; Protein 7-60; Zeta-type opioid receptor
Gene Aliases: OGFR
UniProt ID: (Human) Q9NZT2
Entrez Gene ID: (Human) 11054
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