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Search Thermo Fisher Scientific
Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (55%), Rat (55%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63724. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Olfactory receptors are G protein-coupled receptor proteins that localize to the cilia of olfactory sensory neurons where they display affinity for and bind to a variety of odor molecules. The genes encoding olfactory receptors comprise the largest family in the human genome. The binding of olfactory receptor proteins to odor molecules triggers a signal transduction cascade that leads to the production of cAMP via an olfactory-enriched adenylate cyclase. This event ultimately leads to transmission of action potentials to the brain and the subsequent perception of smell. OR4B1 (Olfactory receptor 4B1), also known as Olfactory receptor OR11-106, is a 309 amino acid multi-pass membrane protein that functions as an odorant receptor, effectively binding odor molecules and initiating the propagation of signals to the primary olfactory cortex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Olfactory receptor 4B1; Olfactory receptor OR11-106; olfactory receptor, family 4, subfamily B, member 1; OST208
Gene Aliases: OR11-106; OR4B1; OST208
UniProt ID: (Human) Q8NGF8
Entrez Gene ID: (Human) 119765
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