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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (84%), Rat (84%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-82341. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
OXSR1 serine/threonine kinase or (OSR1) is activated by osmotic stresses and regulates downstream protein kinases such as PAK1 in order to establish the sensor/signaling modules that initiate the cellular response to environmental stress. OXSR1 can be phosphorylated by ATM or ATR during the DNA damage process. It regulates downstream kinases in response to environmental stress, and may play a role in regulating the actin cytoskeleton.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C6orf182; CEP57R; OTTHUMP00000209062; Oxidative stress-responsive 1 protein; oxidative-stress responsive 1; OXSR1; Serine/threonine-protein kinase OSR1
Gene Aliases: KIAA1101; OSR1; OXSR1
UniProt ID: (Human) O95747
Entrez Gene ID: (Human) 9943
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