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Highest antigen sequence indentity to the following orthologs: Mouse (85%), Rat (85%).
This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Hcrt receptor 1; hypocretin (orexin) receptor 1; Hypocretin receptor type 1; hypocretin receptor-1; Orexin a receptor; orexin receptor 1; Orexin receptor type 1; orexin receptor-1; Orexin-1 receptor; Orexin/Hypocretin receptor type 1; Ox-1-R; OX-R1; OX1 receptor; ox1-R
Gene Aliases: HCRTR1; OX1R
UniProt ID: (Human) O43613
Entrez Gene ID: (Human) 3061
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