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Invitrogen
Human PAQR6 (aa 146-225) Control Fragment Recombinant Protein
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Product Details
RP-105580
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
YIGEGTPGPAREEAGADAFPEHRMNWATATSYSTSVQCWAPTSSWRQCWLIWDHAEPGWPHRNLPWAWQAQWPHWSWLQL
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
1M urea/PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (26%), Rat (26%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-67298. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
Plasma membrane progesterone (P4) receptor coupled to G proteins (PubMed:23763432, PubMed:23161870). Seems to act through a G(s) mediated pathway (PubMed:23161870). Involved in neurosteroid inhibition of apoptosis (PubMed:23161870). May be involved in regulating rapid P4 signaling in the nervous system (PubMed:23763432). Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone (PubMed:23763432, PubMed:23161870). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ22672; Membrane progesterone P4 receptor delta; Membrane progesterone receptor delta; Membrane progestin receptor delta; mPR delta; Progesterone and adipoQ receptor family member 6; Progestin and adipoQ receptor family member 6; progestin and adipoQ receptor family member VI variant 3; progestin and adipoQ receptor family member VI variant 4; progestin and adipoQ receptor family member VI variant 5
Gene Aliases: PAQR6; PRdelta
UniProt ID: (Human) Q6TCH4
Entrez Gene ID: (Human) 79957
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