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Invitrogen
Human RCBTB1 (aa 391-421) Control Fragment Recombinant Protein
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Product Details
RP-105051
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
RCEHFRSMFQSYWNEDMKEVIEIDQFSYPVY
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
1M urea/PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-66040. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
This gene encodes a protein with an N-terminal RCC1 domain and a C-terminal BTB (broad complex, tramtrack and bric-a-brac) domain. In rat, over-expression of this gene in vascular smooth muscle cells induced cellular hypertrophy. In rat, the C-terminus of RCBTB1 interacts with the angiotensin II receptor-1A. In humans, this gene maps to a region of chromosome 13q that is frequently deleted in B-cell chronic lymphocytic leukemia and other lymphoid malignancies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Chronic lymphocytic leukemia deletion region gene 7 protein; CLL deletion region gene 7 protein; GDP/GTP exchange factor (GEF)-like protein; RCC1 and BTB domain-containing protein 1; regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1; Regulator of chromosome condensation and BTB domain-containing protein 1; RP11-185C18.1
Gene Aliases: CLLD7; CLLL7; E4.5; GLP; RCBTB1
UniProt ID: (Human) Q8NDN9
Entrez Gene ID: (Human) 55213
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