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Invitrogen
Human RGP1 (aa 1-96) Control Fragment Recombinant Protein
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Product Details
RP-92905
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
MIEVVAELSRGPVFLAGEALECVVTVTNPLPPTATSASSEALAWASAQIHCQFHASESRVALPPPDSSQPDVQPDSQTVFLPHRGERGQCILSTPP
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-54201. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
Retrograde golgi transport homolog 1 (RGP1) is the mammalian homolog to the yeast RGP1, a protein that forms a tight complex with RIC1. This complex binds Ypt6p and stimulates guanine nucleotide exchange. RGP1 is localized to the Golgi and is thought to be a potential Golgi recycling factor. Rgp1 yeast mutants exhibit defects in retrograde trafficking similar to those seen in yeast with mutations in other retrograde Golgi transport proteins. It is expected that RGP1 plays a similar role in mammalian cells to that seen in yeast.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: RAB6A-GEF complex partner protein 2; Retrograde Golgi transport protein RGP1 homolog; RGP1 (HGNC:21965); RGP1 retrograde golgi transport homolog
Gene Aliases: KIAA0258; RGP1
UniProt ID: (Human) Q92546
Entrez Gene ID: (Human) 9827
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