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Highest antigen sequence indentity to the following orthologs: Mouse (46%), Rat (46%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-60986. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene is similar to a sea urchin radial spoke head protein. Radial spoke protein complexes form part of the axoneme of eukaryotic flagella and are located between the axoneme's outer ring of doublet microtubules and central pair of microtubules. In Chlamydomonas, radial spoke proteins are thought to regulate the activity of dynein and the symmetry of flagellar bending patterns. This gene maps to a region of chromosome 19 that is linked to primary ciliary dyskinesia-2 (CILD2).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ortholog of mouse radial spokehead-like 1; Radial spoke head protein 6 homolog A; Radial spoke head-like protein 1; radial spokehead-like 1
Gene Aliases: RSHL1; RSP4; RSP6; RSPH4B; RSPH6A
UniProt ID: (Human) Q9H0K4
Entrez Gene ID: (Human) 81492
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