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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (97%), Rat (97%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-52177. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
SEPT6 is a member of the septin family of GTPases. Members of this family are required for cytokinesis. This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 2-Sep; 6-Sep; MGC16619; MGC20339; RP5-876A24.2; septin 2; Septin-6
Gene Aliases: KIAA0128; SEP2; SEPT2; SEPT6; SEPTIN6
UniProt ID: (Human) Q14141
Entrez Gene ID: (Human) 23157
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