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This peptide corresponds to 22 amino acids near the center of human SHISA9.
PEP-1172 can be used as a blocking peptide with polyclonal antibody PA5-21058.
Shisa proteins are a recently-identified family of modulators of both FGF and Wnt signaling that block both maturation and transport to the cell surface of their respective receptors. SHISA9, also known as CKAMP44a, is a brain-specific type I transmembrane protein that associates with AMPA receptors in synaptic spines and promotes AMPA receptor desensitization at excitatory synapses. It is thought to modulate short-term plasticity at specific excitatory synapses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cystine-knot AMPAR modulating protein; Protein shisa-9; shisa homolog 9
Gene Aliases: CKAMP44; SHISA9
UniProt ID: (Human) B4DS77
Entrez Gene ID: (Human) 729993
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