Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (91%), Rat (91%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-57435. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The SIDT1 gene encodes the SID1 transmembrane family member 1 protein, which is involved in RNA transport and may play a role in RNA silencing pathways. SIDT1 has been studied for its role in facilitating the uptake and cellular exchange of double-stranded RNA (dsRNA), a process that is crucial for gene regulation and immune responses. The protein's activity is thought to be involved in RNA interference (RNAi), a mechanism for silencing genes that are complementary to an introduced dsRNA. SIDT1's function is important for maintaining RNA homeostasis and regulating gene expression, impacting various cellular processes and potential therapeutic applications, such as antiviral strategies and cancer treatment. Understanding the role of SIDT1 in RNA transport and the RNAi pathway provides insights into how cells manage genetic and environmental information, which could be pivotal for developing RNA-based therapeutic interventions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: SID1 transmembrane family member 1; SID1 transmembrane family, member 1
Gene Aliases: SID-1; SID1; SIDT1
UniProt ID: (Human) Q9NXL6
Entrez Gene ID: (Human) 54847
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