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Search Thermo Fisher Scientific
Invitrogen
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This peptide corresponds to 14 amino acid peptide near the amino terminus of human SLAIN2.
PEP-1458 can be used as a blocking peptide with polyclonal antibody PA5-34416.
SLAIN2 is closely related to SLAIN1, a novel stem cell protein that is expressed at the stem cell and epiblast stages. Unlike SLAIN1, SLAIN2 is widely expressed and is thought to play a role in regulating microtubule (MT) growth and organization. SLAIN2 binds to end-binding proteins (EBs), cytoplasmic linker proteins (CLIPs) such as CLIP170, CLIP-associated proteins, and interacts with the MT polymerase ch-TOG. Depletion of SLAIN2 using RNAi led to disorganization of the radial MT array, indicating its importance in the regulation of MT growth and organization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FLJ21611; SLAIN motif family, member 2; SLAIN motif-containing protein 2
Gene Aliases: KIAA1458; SLAIN2
UniProt ID: (Human) Q9P270
Entrez Gene ID: (Human) 57606
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