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Search Thermo Fisher Scientific
Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-144765. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). The encoded protein, which is a member of glycosyltransferase family 29, is a type II membrane protein that may be present in the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Alpha-2,8-sialyltransferase 8D; CMP-N-acetylneuraminate-poly-alpha-2,8-sialyl transferase; CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase; Polysialyltransferase; Polysialyltransferase-1; sialyltransf; sialyltransferase 8 (alpha-2, 8-polysialytransferase) D; Sialyltransferase 8D; Sialyltransferase St8Sia IV; sialytransferase St8Sia IV; SIAT8-D; ST8 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase 4; ST8SiaIV
Gene Aliases: PST; PST1; SIAT8D; ST8SIA-IV; ST8SIA4
UniProt ID: (Human) Q92187
Entrez Gene ID: (Human) 7903
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