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Invitrogen
Human SVOPL (aa 223-282) Control Fragment Recombinant Protein
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Product Details
RP-91260
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
PESARFNVSTGNTRAALATLERVAKMNRSVMPEGKLVEPVLEKRGRFADLLDAKYLRTTL
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
1M urea/PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (88%), Rat (88%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-53710. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
SVOPL (putative transporter SVOPL), also known as SV2-related protein-like, is a 492 amino acid multi-pass membrane protein belonging to the major facilitator superfamily. SVOPL is a paralog to synaptic vesicle protein (SVOP) that exists as two alternatively spliced isoforms. The gene encoding SVOPL maps to human chromosome 7q34. Chromosome 7 is approximately 158 milllion bases long, encodes over 1,000 genes and makes up approximately 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. Deletions of portions of the q arm of chromosome 7 are linked to myeloid disorders, including acute myelogenous leukemia and myelodysplasia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Putative transporter SVOPL; SV2 related protein homolog-like; SV2-related protein-like; SVOP-like; SVOP-like protein
Gene Aliases: SVOPL
UniProt ID: (Human) Q8N434
Entrez Gene ID: (Human) 136306
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