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Invitrogen
Human TAFA3 (aa 30-50) Control Fragment Recombinant Protein
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Product Details
RP-101557
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
AALQPPTATVLVQQGTCEVIA
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (81%), Rat (81%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63210. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
The TAFA3 gene encodes a protein that is part of the TAFA family of chemokine-like proteins, involved in modulating immune responses and inflammatory processes. TAFA3 is particularly implicated in the regulation of neuroinflammatory and neuroprotective activities in the central nervous system. It functions as a signaling molecule that can influence cell survival, proliferation, and migration, contributing to homeostasis in neural tissue and promoting recovery following injury. TAFA3 has been studied for its role in neuroprotection, where it helps shield neurons from damage caused by oxidative stress and inflammatory stimuli, making it significant in neurodegenerative conditions. Apart from its neuroprotective capabilities, TAFA3 may also be involved in the systemic modulation of inflammation, affecting immune cell trafficking and responses. Research into TAFA3 continues to unveil its multifaceted role in health and disease, highlighting potential therapeutic avenues for targeting this protein in conditions characterized by excessive inflammation or neurodegeneration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Chemokine-like protein TAFA-3; family with sequence similarity 19 (chemokine (C-C motif)-like), member A3
Gene Aliases: FAM19A3; TAFA-3; TAFA3
UniProt ID: (Human) Q7Z5A8
Entrez Gene ID: (Human) 284467
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