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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (72%), Rat (72%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-82161. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene consists of two polypeptide chains activated from a single precursor protein by proteolysis. The encoded protein is involved the later stages of cell envelope formation in the epidermis and hair follicle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: E polypeptide, protein-glutamine-gamma-glutamyltransferase; MGC126249; MGC126250; Protein-glutamine gamma-glutamyltransferase E; TG(E); TGase E; TGase TGase-3; TGase-3; Transglutaminase E; Transglutaminase-3
Gene Aliases: TGE; TGM3
UniProt ID: (Human) Q08188
Entrez Gene ID: (Human) 7053
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