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Invitrogen
Human TOMM20L (aa 38-90) Control Fragment Recombinant Protein
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Product Details
RP-109553
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
AFKRRLRDKRRAEPQKAEEQGTQLWDPTKNKKLQELFLQEVRMGELWLSRGEH
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (58%), Rat (58%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-140283. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
The TOMM20L gene encodes a protein that is highly related to the translocase of outer mitochondria membrane 20 homolog (TOMM20), which plays a crucial role in the import of mitochondrial preproteins. TOMM20L, likely a paralog or isoform of TOMM20, shares functional similarities and contributes to the complex processes facilitating protein translocation across the outer mitochondrial membrane. This gene's product is integral to the translocase of the outer mitochondrial membrane (TOM) complex, which is essential for maintaining mitochondrial function and biogenesis. TOMM20L assists in the recognition and import of cytosolic precursor proteins into the mitochondria, influencing mitochondrial assembly and function. Although the specific functions of TOMM20L compared to TOMM20 require further elucidation, it is presumed to modulate mitochondrial dynamics and physiology. Alterations in TOMM20L expression could impact mitochondrial efficiency and are relevant in conditions related to energy metabolism and mitochondrial disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: TOMM20-like protein 1; translocase of outer mitochondrial membrane 20 homolog (yeast)-like; translocase of outer mitochondrial membrane 20 homolog type I
Gene Aliases: TOMM20L; UNQ9438; UNQ9438/PRO34772
UniProt ID: (Human) Q6UXN7
Entrez Gene ID: (Human) 387990
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